Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells

The methylation of non-CpG residues is a poorly understood marker of pluripotent cells, gradually lost as cells differentiate. Here the authors show non-CG methylation can be used as a marker of differentiation potential.

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Autores principales:	Lee M. Butcher, Mitsuteru Ito, Minodora Brimpari, Tiffany J. Morris, Filipa A. C. Soares, Lars Ährlund-Richter, Nessa Carey, Ludovic Vallier, Anne C. Ferguson-Smith, Stephan Beck
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a75d99cb5a2a420d8e54b0606e20b5bf
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spelling	oai:doaj.org-article:a75d99cb5a2a420d8e54b0606e20b5bf2021-12-02T14:39:49ZNon-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells10.1038/ncomms104582041-1723https://doaj.org/article/a75d99cb5a2a420d8e54b0606e20b5bf2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10458https://doaj.org/toc/2041-1723The methylation of non-CpG residues is a poorly understood marker of pluripotent cells, gradually lost as cells differentiate. Here the authors show non-CG methylation can be used as a marker of differentiation potential.Lee M. ButcherMitsuteru ItoMinodora BrimpariTiffany J. MorrisFilipa A. C. SoaresLars Ährlund-RichterNessa CareyLudovic VallierAnne C. Ferguson-SmithStephan BeckNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lee M. Butcher Mitsuteru Ito Minodora Brimpari Tiffany J. Morris Filipa A. C. Soares Lars Ährlund-Richter Nessa Carey Ludovic Vallier Anne C. Ferguson-Smith Stephan Beck Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells
description	The methylation of non-CpG residues is a poorly understood marker of pluripotent cells, gradually lost as cells differentiate. Here the authors show non-CG methylation can be used as a marker of differentiation potential.
format	article
author	Lee M. Butcher Mitsuteru Ito Minodora Brimpari Tiffany J. Morris Filipa A. C. Soares Lars Ährlund-Richter Nessa Carey Ludovic Vallier Anne C. Ferguson-Smith Stephan Beck
author_facet	Lee M. Butcher Mitsuteru Ito Minodora Brimpari Tiffany J. Morris Filipa A. C. Soares Lars Ährlund-Richter Nessa Carey Ludovic Vallier Anne C. Ferguson-Smith Stephan Beck
author_sort	Lee M. Butcher
title	Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells
title_short	Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells
title_full	Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells
title_fullStr	Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells
title_full_unstemmed	Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells
title_sort	non-cg dna methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/a75d99cb5a2a420d8e54b0606e20b5bf
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Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells

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