Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells

Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells

The methylation of non-CpG residues is a poorly understood marker of pluripotent cells, gradually lost as cells differentiate. Here the authors show non-CG methylation can be used as a marker of differentiation potential.

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Autores principales: Lee M. Butcher, Mitsuteru Ito, Minodora Brimpari, Tiffany J. Morris, Filipa A. C. Soares, Lars Ährlund-Richter, Nessa Carey, Ludovic Vallier, Anne C. Ferguson-Smith, Stephan Beck
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
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Acceso en línea:https://doaj.org/article/a75d99cb5a2a420d8e54b0606e20b5bf
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