Transient auditory nerve demyelination as a new mechanism for hidden hearing loss

Hidden hearing loss (HHL) is an auditory neuropathy that impairs one’s ability to hear, particularly in a noisy environment. Here the authors show that in mice, transient loss of cochlear Schwann cells results in permanent disruption of the cochlear heminodal structure, leading to auditory deficits...

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Autores principales: Guoqiang Wan, Gabriel Corfas
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/a76b0ae510f1456aa2eb07e7b1426e80
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spelling oai:doaj.org-article:a76b0ae510f1456aa2eb07e7b1426e802021-12-02T15:38:57ZTransient auditory nerve demyelination as a new mechanism for hidden hearing loss10.1038/ncomms144872041-1723https://doaj.org/article/a76b0ae510f1456aa2eb07e7b1426e802017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14487https://doaj.org/toc/2041-1723Hidden hearing loss (HHL) is an auditory neuropathy that impairs one’s ability to hear, particularly in a noisy environment. Here the authors show that in mice, transient loss of cochlear Schwann cells results in permanent disruption of the cochlear heminodal structure, leading to auditory deficits characteristic of HHL.Guoqiang WanGabriel CorfasNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Guoqiang Wan
Gabriel Corfas
Transient auditory nerve demyelination as a new mechanism for hidden hearing loss
description Hidden hearing loss (HHL) is an auditory neuropathy that impairs one’s ability to hear, particularly in a noisy environment. Here the authors show that in mice, transient loss of cochlear Schwann cells results in permanent disruption of the cochlear heminodal structure, leading to auditory deficits characteristic of HHL.
format article
author Guoqiang Wan
Gabriel Corfas
author_facet Guoqiang Wan
Gabriel Corfas
author_sort Guoqiang Wan
title Transient auditory nerve demyelination as a new mechanism for hidden hearing loss
title_short Transient auditory nerve demyelination as a new mechanism for hidden hearing loss
title_full Transient auditory nerve demyelination as a new mechanism for hidden hearing loss
title_fullStr Transient auditory nerve demyelination as a new mechanism for hidden hearing loss
title_full_unstemmed Transient auditory nerve demyelination as a new mechanism for hidden hearing loss
title_sort transient auditory nerve demyelination as a new mechanism for hidden hearing loss
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/a76b0ae510f1456aa2eb07e7b1426e80
work_keys_str_mv AT guoqiangwan transientauditorynervedemyelinationasanewmechanismforhiddenhearingloss
AT gabrielcorfas transientauditorynervedemyelinationasanewmechanismforhiddenhearingloss
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