Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis

Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis

Patients with rheumatoid arthritis are commonly stratified by ACPA serology, with positivity being associated with more severe disease and joint destruction. Here the authors present a single cell RNA sequencing resource comparing peripheral blood and synovial tissue cells from patients with ACPA+ v...

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Autores principales: Xunyao Wu, Yi Liu, Shanzhao Jin, Min Wang, Yuhao Jiao, Bo Yang, Xin Lu, Xin Ji, Yunyun Fei, Huaxia Yang, Lidan Zhao, Hua Chen, Yaran Zhang, Hao Li, Peter E. Lipsky, George C. Tsokos, Fan Bai, Xuan Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a76d17f2901f409b96a7a520d3bb90cf
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spelling oai:doaj.org-article:a76d17f2901f409b96a7a520d3bb90cf2021-12-02T15:10:40ZSingle-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis10.1038/s41467-021-25246-72041-1723https://doaj.org/article/a76d17f2901f409b96a7a520d3bb90cf2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25246-7https://doaj.org/toc/2041-1723Patients with rheumatoid arthritis are commonly stratified by ACPA serology, with positivity being associated with more severe disease and joint destruction. Here the authors present a single cell RNA sequencing resource comparing peripheral blood and synovial tissue cells from patients with ACPA+ versus ACPA- rheumatoid arthritis.Xunyao WuYi LiuShanzhao JinMin WangYuhao JiaoBo YangXin LuXin JiYunyun FeiHuaxia YangLidan ZhaoHua ChenYaran ZhangHao LiPeter E. LipskyGeorge C. TsokosFan BaiXuan ZhangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xunyao Wu
Yi Liu
Shanzhao Jin
Min Wang
Yuhao Jiao
Bo Yang
Xin Lu
Xin Ji
Yunyun Fei
Huaxia Yang
Lidan Zhao
Hua Chen
Yaran Zhang
Hao Li
Peter E. Lipsky
George C. Tsokos
Fan Bai
Xuan Zhang
Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis
description Patients with rheumatoid arthritis are commonly stratified by ACPA serology, with positivity being associated with more severe disease and joint destruction. Here the authors present a single cell RNA sequencing resource comparing peripheral blood and synovial tissue cells from patients with ACPA+ versus ACPA- rheumatoid arthritis.
format article
author Xunyao Wu
Yi Liu
Shanzhao Jin
Min Wang
Yuhao Jiao
Bo Yang
Xin Lu
Xin Ji
Yunyun Fei
Huaxia Yang
Lidan Zhao
Hua Chen
Yaran Zhang
Hao Li
Peter E. Lipsky
George C. Tsokos
Fan Bai
Xuan Zhang
author_facet Xunyao Wu
Yi Liu
Shanzhao Jin
Min Wang
Yuhao Jiao
Bo Yang
Xin Lu
Xin Ji
Yunyun Fei
Huaxia Yang
Lidan Zhao
Hua Chen
Yaran Zhang
Hao Li
Peter E. Lipsky
George C. Tsokos
Fan Bai
Xuan Zhang
author_sort Xunyao Wu
title Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis
title_short Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis
title_full Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis
title_fullStr Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis
title_full_unstemmed Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis
title_sort single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a76d17f2901f409b96a7a520d3bb90cf
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