Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

Recent studies suggest key roles of RNA in DNA double-strand breaks repair. Here the authors identify the helicase senataxin to be involved in DNA repair and resolve RNA:DNA hybrids forming at DNA double-strand breaks.

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Autores principales:	Sarah Cohen, Nadine Puget, Yea-Lih Lin, Thomas Clouaire, Marion Aguirrebengoa, Vincent Rocher, Philippe Pasero, Yvan Canitrot, Gaëlle Legube
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a76ef802a4c44fb2b9db439a268bff73
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spelling	oai:doaj.org-article:a76ef802a4c44fb2b9db439a268bff732021-12-02T16:50:10ZSenataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations10.1038/s41467-018-02894-w2041-1723https://doaj.org/article/a76ef802a4c44fb2b9db439a268bff732018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02894-whttps://doaj.org/toc/2041-1723Recent studies suggest key roles of RNA in DNA double-strand breaks repair. Here the authors identify the helicase senataxin to be involved in DNA repair and resolve RNA:DNA hybrids forming at DNA double-strand breaks.Sarah CohenNadine PugetYea-Lih LinThomas ClouaireMarion AguirrebengoaVincent RocherPhilippe PaseroYvan CanitrotGaëlle LegubeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sarah Cohen Nadine Puget Yea-Lih Lin Thomas Clouaire Marion Aguirrebengoa Vincent Rocher Philippe Pasero Yvan Canitrot Gaëlle Legube Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations
description	Recent studies suggest key roles of RNA in DNA double-strand breaks repair. Here the authors identify the helicase senataxin to be involved in DNA repair and resolve RNA:DNA hybrids forming at DNA double-strand breaks.
format	article
author	Sarah Cohen Nadine Puget Yea-Lih Lin Thomas Clouaire Marion Aguirrebengoa Vincent Rocher Philippe Pasero Yvan Canitrot Gaëlle Legube
author_facet	Sarah Cohen Nadine Puget Yea-Lih Lin Thomas Clouaire Marion Aguirrebengoa Vincent Rocher Philippe Pasero Yvan Canitrot Gaëlle Legube
author_sort	Sarah Cohen
title	Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations
title_short	Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations
title_full	Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations
title_fullStr	Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations
title_full_unstemmed	Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations
title_sort	senataxin resolves rna:dna hybrids forming at dna double-strand breaks to prevent translocations
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/a76ef802a4c44fb2b9db439a268bff73
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Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

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