Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

Recent studies suggest key roles of RNA in DNA double-strand breaks repair. Here the authors identify the helicase senataxin to be involved in DNA repair and resolve RNA:DNA hybrids forming at DNA double-strand breaks.

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Autores principales: Sarah Cohen, Nadine Puget, Yea-Lih Lin, Thomas Clouaire, Marion Aguirrebengoa, Vincent Rocher, Philippe Pasero, Yvan Canitrot, Gaëlle Legube
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
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Acceso en línea:https://doaj.org/article/a76ef802a4c44fb2b9db439a268bff73
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