Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features

Objective. This case involves a new-onset diabetes patient diagnosed during pregnancy with the congenital dysplastic right kidney. Case Report. Clinical presentation, biochemical features, imaging in a patient with diabetes diagnosed during pregnancy, and congenital dysplastic right kidney. Discussi...

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Autores principales:	Adnan Haider, Oksana Symczyk, Ayesha Hassan, Muhammad Atif Khan, Inderpreet Madahar, Dylan Holland
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/a779dd2aef7a41b080829c667edf91dd
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spelling	oai:doaj.org-article:a779dd2aef7a41b080829c667edf91dd2021-11-22T01:10:37ZMaturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features2090-651X10.1155/2021/8243471https://doaj.org/article/a779dd2aef7a41b080829c667edf91dd2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/8243471https://doaj.org/toc/2090-651XObjective. This case involves a new-onset diabetes patient diagnosed during pregnancy with the congenital dysplastic right kidney. Case Report. Clinical presentation, biochemical features, imaging in a patient with diabetes diagnosed during pregnancy, and congenital dysplastic right kidney. Discussion. We present a case of a 22-year-old female with the congenital dysplastic right kidney diagnosed with gestational diabetes mellitus after failing a 1-hour oral glucose tolerance test, requiring insulin during pregnancy. Because of the family history of diabetes and morphologic renal abnormalities at young ages on the maternal side of the family, our patient was evaluated for maturity-onset diabetes of adult and was found to have HNF-1β mutation. Conclusion. This case highlights the importance of considering the diagnosis of maturity-onset diabetes of young and particularly MODY-5 in individuals with extrapancreatic features. MODY-5 should also be considered in a patient undergoing renal transplant at young ages with a family history of morphologic renal abnormalities.Adnan HaiderOksana SymczykAyesha HassanMuhammad Atif KhanInderpreet MadaharDylan HollandHindawi LimitedarticleDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENCase Reports in Endocrinology, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	Diseases of the endocrine glands. Clinical endocrinology RC648-665 Adnan Haider Oksana Symczyk Ayesha Hassan Muhammad Atif Khan Inderpreet Madahar Dylan Holland Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features
description	Objective. This case involves a new-onset diabetes patient diagnosed during pregnancy with the congenital dysplastic right kidney. Case Report. Clinical presentation, biochemical features, imaging in a patient with diabetes diagnosed during pregnancy, and congenital dysplastic right kidney. Discussion. We present a case of a 22-year-old female with the congenital dysplastic right kidney diagnosed with gestational diabetes mellitus after failing a 1-hour oral glucose tolerance test, requiring insulin during pregnancy. Because of the family history of diabetes and morphologic renal abnormalities at young ages on the maternal side of the family, our patient was evaluated for maturity-onset diabetes of adult and was found to have HNF-1β mutation. Conclusion. This case highlights the importance of considering the diagnosis of maturity-onset diabetes of young and particularly MODY-5 in individuals with extrapancreatic features. MODY-5 should also be considered in a patient undergoing renal transplant at young ages with a family history of morphologic renal abnormalities.
format	article
author	Adnan Haider Oksana Symczyk Ayesha Hassan Muhammad Atif Khan Inderpreet Madahar Dylan Holland
author_facet	Adnan Haider Oksana Symczyk Ayesha Hassan Muhammad Atif Khan Inderpreet Madahar Dylan Holland
author_sort	Adnan Haider
title	Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features
title_short	Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features
title_full	Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features
title_fullStr	Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features
title_full_unstemmed	Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features
title_sort	maturity-onset diabetes of young type 5: diabetes with extrapancreatic features
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/a779dd2aef7a41b080829c667edf91dd
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Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features

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