Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge
The small molecule Nobiletin enhances circadian rhythms and protects against obesity-associated metabolic dysfunction in mice. Here the authors test its effect on health and lifespan, reporting that circadian enhancement promotes fitness and healthy aging in metabolically challenged mice.
Guardado en:
Autores principales: | Kazunari Nohara, Venkata Mallampalli, Travis Nemkov, Marvin Wirianto, Jiah Yang, Youqiong Ye, Yuxiang Sun, Leng Han, Karyn A. Esser, Eugenia Mileykovskaya, Angelo D’Alessandro, Carla B. Green, Joseph S. Takahashi, William Dowhan, Seung-Hee Yoo, Zheng Chen |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/a785be3a47764eeebef82872ff3d00a8 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Transdermal delivery of nobiletin using ionic liquids
por: Tadashi Hattori, et al.
Publicado: (2019) -
A study on the curative effect of nobiletin on paraquat induced toxicity in rat
por: Muhammad Umar Ijaz, et al.
Publicado: (2022) -
The pharmacokinetic study on the interaction between nobiletin and anemarsaponin BII in vivo and in vitro
por: Jie Zhang, et al.
Publicado: (2021) -
Nobiletin-loaded micelles reduce ovariectomy-induced bone loss by suppressing osteoclastogenesis
por: Wang Y, et al.
Publicado: (2019) -
The Response of Mitochondrial Respiration and Quantity in Skeletal Muscle and Adipose Tissue to Exercise in Humans with Prediabetes
por: Lukasz Szczerbinski, et al.
Publicado: (2021)