When algorithms falter: a case report of a very small melanoma excised due to the dermatoscopic “ugly duckling” sign

We present a case report of a 3.5 mm diameter superficial spreading melanoma on the upper back of a 27-year-old woman, signed out as Clark level 2, Breslow thickness 0.2 mm with regression to 0.45 mm. The patient, with Fitzpatrick type 1 skin and minimal actinic damage, had presented for a routine...

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Autores principales:	Mike Inskip, Jill Magee, David Weedon, Cliff Rosendahl
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2013
Materias:	dermatoscopy superficial spreading melanoma melanoma small melanoma ugly duckling sign Ewing's sarcoma Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/a785ffbff3d24ed3b677a64598d817a4
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spelling	oai:doaj.org-article:a785ffbff3d24ed3b677a64598d817a42021-11-17T08:32:49ZWhen algorithms falter: a case report of a very small melanoma excised due to the dermatoscopic “ugly duckling” sign10.5826/dpc.0302a092160-9381https://doaj.org/article/a785ffbff3d24ed3b677a64598d817a42013-04-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/957https://doaj.org/toc/2160-9381 We present a case report of a 3.5 mm diameter superficial spreading melanoma on the upper back of a 27-year-old woman, signed out as Clark level 2, Breslow thickness 0.2 mm with regression to 0.45 mm. The patient, with Fitzpatrick type 1 skin and minimal actinic damage, had presented for a routine skin check with no previous history of skin cancers. At the age of 17 she had received chemotherapy and radiotherapy for Ewing’s sarcoma of the right hip with pulmonary metastases. The skin lesion was assessed as dermatoscopically symmetrical and was not predicted as a melanoma by any algorithmic method. The provisional diagnosis of melanoma was made on the basis that this lesion was completely different in dermatoscopic pattern to her other nevi, a dermatoscopic “ugly duckling” lesion. We draw attention to the recently established link between defects in the STAG2 gene and Ewing’s sarcoma, glioblastoma and melanoma. Mike InskipJill MageeDavid WeedonCliff RosendahlMattioli1885articledermatoscopysuperficial spreading melanomamelanomasmall melanomaugly duckling signEwing's sarcomaDermatologyRL1-803ENDermatology Practical & Conceptual (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	dermatoscopy superficial spreading melanoma melanoma small melanoma ugly duckling sign Ewing's sarcoma Dermatology RL1-803
spellingShingle	dermatoscopy superficial spreading melanoma melanoma small melanoma ugly duckling sign Ewing's sarcoma Dermatology RL1-803 Mike Inskip Jill Magee David Weedon Cliff Rosendahl When algorithms falter: a case report of a very small melanoma excised due to the dermatoscopic “ugly duckling” sign
description	We present a case report of a 3.5 mm diameter superficial spreading melanoma on the upper back of a 27-year-old woman, signed out as Clark level 2, Breslow thickness 0.2 mm with regression to 0.45 mm. The patient, with Fitzpatrick type 1 skin and minimal actinic damage, had presented for a routine skin check with no previous history of skin cancers. At the age of 17 she had received chemotherapy and radiotherapy for Ewing’s sarcoma of the right hip with pulmonary metastases. The skin lesion was assessed as dermatoscopically symmetrical and was not predicted as a melanoma by any algorithmic method. The provisional diagnosis of melanoma was made on the basis that this lesion was completely different in dermatoscopic pattern to her other nevi, a dermatoscopic “ugly duckling” lesion. We draw attention to the recently established link between defects in the STAG2 gene and Ewing’s sarcoma, glioblastoma and melanoma.
format	article
author	Mike Inskip Jill Magee David Weedon Cliff Rosendahl
author_facet	Mike Inskip Jill Magee David Weedon Cliff Rosendahl
author_sort	Mike Inskip
title	When algorithms falter: a case report of a very small melanoma excised due to the dermatoscopic “ugly duckling” sign
title_short	When algorithms falter: a case report of a very small melanoma excised due to the dermatoscopic “ugly duckling” sign
title_full	When algorithms falter: a case report of a very small melanoma excised due to the dermatoscopic “ugly duckling” sign
title_fullStr	When algorithms falter: a case report of a very small melanoma excised due to the dermatoscopic “ugly duckling” sign
title_full_unstemmed	When algorithms falter: a case report of a very small melanoma excised due to the dermatoscopic “ugly duckling” sign
title_sort	when algorithms falter: a case report of a very small melanoma excised due to the dermatoscopic “ugly duckling” sign
publisher	Mattioli1885
publishDate	2013
url	https://doaj.org/article/a785ffbff3d24ed3b677a64598d817a4
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When algorithms falter: a case report of a very small melanoma excised due to the dermatoscopic “ugly duckling” sign

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