Cooperativity dominates the genomic organization of p53-response elements: a mechanistic view.

p53-response elements (p53-REs) are organized as two repeats of a palindromic DNA segment spaced by 0 to 20 base pairs (bp). Several experiments indicate that in the vast majority of the human p53-REs there are no spacers between the two repeats; those with spacers, particularly with sizes beyond tw...

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Autores principales: Yongping Pan, Ruth Nussinov
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/a787ec909db64729904d831aed0305f0
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