<named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Pyrazinamide Resistance Determinants: a Multicenter Study
ABSTRACT Pyrazinamide (PZA) is a prodrug that is converted to pyrazinoic acid by the enzyme pyrazinamidase, encoded by the pncA gene in Mycobacterium tuberculosis. Molecular identification of mutations in pncA offers the potential for rapid detection of pyrazinamide resistance (PZAr). However, the g...
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Auteurs principaux: | Paolo Miotto, Andrea M. Cabibbe, Silke Feuerriegel, Nicola Casali, Francis Drobniewski, Yulia Rodionova, Daiva Bakonyte, Petras Stakenas, Edita Pimkina, Ewa Augustynowicz-Kopeć, Massimo Degano, Alessandro Ambrosi, Sven Hoffner, Mikael Mansjö, Jim Werngren, Sabine Rüsch-Gerdes, Stefan Niemann, Daniela M. Cirillo |
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Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2014
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Accès en ligne: | https://doaj.org/article/a793c5931b3743058afca8d56f3a8e4d |
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