<named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Pyrazinamide Resistance Determinants: a Multicenter Study
ABSTRACT Pyrazinamide (PZA) is a prodrug that is converted to pyrazinoic acid by the enzyme pyrazinamidase, encoded by the pncA gene in Mycobacterium tuberculosis. Molecular identification of mutations in pncA offers the potential for rapid detection of pyrazinamide resistance (PZAr). However, the g...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2014
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| Subjects: | |
| Online Access: | https://doaj.org/article/a793c5931b3743058afca8d56f3a8e4d |
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