PILOMATRIX CARCINOMA WAS BEYOND ANY EXPECTATIONS: A CASE REPORT OF CARCINOMA CLINICIAN SHOULD BE AWARE OF IT

Introduction: Pilomatrix carcinoma is a rare cutaneous tumor derived from follicular matrix with about 150 reported cases and it is considered as locally aggressive tumor with a tendency to recur. In addition to lymph node metastases and poor prognosis, it is non-chemotherapy responding in systemic...

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Autores principales:	Abdalraouf Omar, Suad Elnnami, Ibtihaj Hassan
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Diseases of the blood and blood-forming organs RC633-647.5
Acceso en línea:	https://doaj.org/article/a79b44ad98c4489b892584c1fd2c0002
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spelling	oai:doaj.org-article:a79b44ad98c4489b892584c1fd2c00022021-11-10T04:37:57ZPILOMATRIX CARCINOMA WAS BEYOND ANY EXPECTATIONS: A CASE REPORT OF CARCINOMA CLINICIAN SHOULD BE AWARE OF IT2531-137910.1016/j.htct.2021.10.1062https://doaj.org/article/a79b44ad98c4489b892584c1fd2c00022021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2531137921012098https://doaj.org/toc/2531-1379Introduction: Pilomatrix carcinoma is a rare cutaneous tumor derived from follicular matrix with about 150 reported cases and it is considered as locally aggressive tumor with a tendency to recur. In addition to lymph node metastases and poor prognosis, it is non-chemotherapy responding in systemic metastasis. Method and result: A 37-year-old Libyan man presented with two large, coalesced nodules in the face measuring about 32 cm and 33 cm, treated as a case of lipoma by surgical excision based on clinical diagnosis, reappearing of larger nodule 964 cm involving almost all the left check, surgical excision was done with histopathological features of pilomatrix carcinoma infiltrating to the subcutaneous adipose tissue and deep striated muscle with no clear margins. Conventional radiotherapy by electron beam was started using the linear accelerating machine, with total radiotherapy dose 60 gray (Gy) in 30 fraction for six weeks. No local recurrences, nor lymph node or systemic metastasis since June 2020. Conclusion: Pilomatrix carcinoma must always be considered in the differential diagnosis of nodular tumors of the head-and-neck due to high recurrence rate after simple excision. Furthermore, local radiotherapy post incomplete surgical excision is the best adjuvant therapy.Abdalraouf OmarSuad ElnnamiIbtihaj HassanElsevierarticleDiseases of the blood and blood-forming organsRC633-647.5ENHematology, Transfusion and Cell Therapy, Vol 43, Iss , Pp S52- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the blood and blood-forming organs RC633-647.5
spellingShingle	Diseases of the blood and blood-forming organs RC633-647.5 Abdalraouf Omar Suad Elnnami Ibtihaj Hassan PILOMATRIX CARCINOMA WAS BEYOND ANY EXPECTATIONS: A CASE REPORT OF CARCINOMA CLINICIAN SHOULD BE AWARE OF IT
description	Introduction: Pilomatrix carcinoma is a rare cutaneous tumor derived from follicular matrix with about 150 reported cases and it is considered as locally aggressive tumor with a tendency to recur. In addition to lymph node metastases and poor prognosis, it is non-chemotherapy responding in systemic metastasis. Method and result: A 37-year-old Libyan man presented with two large, coalesced nodules in the face measuring about 32 cm and 33 cm, treated as a case of lipoma by surgical excision based on clinical diagnosis, reappearing of larger nodule 964 cm involving almost all the left check, surgical excision was done with histopathological features of pilomatrix carcinoma infiltrating to the subcutaneous adipose tissue and deep striated muscle with no clear margins. Conventional radiotherapy by electron beam was started using the linear accelerating machine, with total radiotherapy dose 60 gray (Gy) in 30 fraction for six weeks. No local recurrences, nor lymph node or systemic metastasis since June 2020. Conclusion: Pilomatrix carcinoma must always be considered in the differential diagnosis of nodular tumors of the head-and-neck due to high recurrence rate after simple excision. Furthermore, local radiotherapy post incomplete surgical excision is the best adjuvant therapy.
format	article
author	Abdalraouf Omar Suad Elnnami Ibtihaj Hassan
author_facet	Abdalraouf Omar Suad Elnnami Ibtihaj Hassan
author_sort	Abdalraouf Omar
title	PILOMATRIX CARCINOMA WAS BEYOND ANY EXPECTATIONS: A CASE REPORT OF CARCINOMA CLINICIAN SHOULD BE AWARE OF IT
title_short	PILOMATRIX CARCINOMA WAS BEYOND ANY EXPECTATIONS: A CASE REPORT OF CARCINOMA CLINICIAN SHOULD BE AWARE OF IT
title_full	PILOMATRIX CARCINOMA WAS BEYOND ANY EXPECTATIONS: A CASE REPORT OF CARCINOMA CLINICIAN SHOULD BE AWARE OF IT
title_fullStr	PILOMATRIX CARCINOMA WAS BEYOND ANY EXPECTATIONS: A CASE REPORT OF CARCINOMA CLINICIAN SHOULD BE AWARE OF IT
title_full_unstemmed	PILOMATRIX CARCINOMA WAS BEYOND ANY EXPECTATIONS: A CASE REPORT OF CARCINOMA CLINICIAN SHOULD BE AWARE OF IT
title_sort	pilomatrix carcinoma was beyond any expectations: a case report of carcinoma clinician should be aware of it
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/a79b44ad98c4489b892584c1fd2c0002
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PILOMATRIX CARCINOMA WAS BEYOND ANY EXPECTATIONS: A CASE REPORT OF CARCINOMA CLINICIAN SHOULD BE AWARE OF IT

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