Pediatric Sarcoma Data Forms a Unique Cluster Measured via the Earth Mover’s Distance

Abstract In this note, we combined pediatric sarcoma data from Columbia University with adult sarcoma data collected from TCGA, in order to see if one can automatically discern a unique pediatric cluster in the combined data set. Using a novel clustering pipeline based on optimal transport theory, t...

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Auteurs principaux:	Yongxin Chen, Filemon Dela Cruz, Romeil Sandhu, Andrew L. Kung, Prabhjot Mundi, Joseph O. Deasy, Allen Tannenbaum
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Medicine R Science Q
Accès en ligne:	https://doaj.org/article/a79b7a3d0c4e4c8f9950c14e91f13336
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id	oai:doaj.org-article:a79b7a3d0c4e4c8f9950c14e91f13336
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spelling	oai:doaj.org-article:a79b7a3d0c4e4c8f9950c14e91f133362021-12-02T15:05:13ZPediatric Sarcoma Data Forms a Unique Cluster Measured via the Earth Mover’s Distance10.1038/s41598-017-07551-82045-2322https://doaj.org/article/a79b7a3d0c4e4c8f9950c14e91f133362017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07551-8https://doaj.org/toc/2045-2322Abstract In this note, we combined pediatric sarcoma data from Columbia University with adult sarcoma data collected from TCGA, in order to see if one can automatically discern a unique pediatric cluster in the combined data set. Using a novel clustering pipeline based on optimal transport theory, this turned out to be the case. The overall methodology may find uses for the classification of data from other biological networking problems.Yongxin ChenFilemon Dela CruzRomeil SandhuAndrew L. KungPrabhjot MundiJoseph O. DeasyAllen TannenbaumNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yongxin Chen Filemon Dela Cruz Romeil Sandhu Andrew L. Kung Prabhjot Mundi Joseph O. Deasy Allen Tannenbaum Pediatric Sarcoma Data Forms a Unique Cluster Measured via the Earth Mover’s Distance
description	Abstract In this note, we combined pediatric sarcoma data from Columbia University with adult sarcoma data collected from TCGA, in order to see if one can automatically discern a unique pediatric cluster in the combined data set. Using a novel clustering pipeline based on optimal transport theory, this turned out to be the case. The overall methodology may find uses for the classification of data from other biological networking problems.
format	article
author	Yongxin Chen Filemon Dela Cruz Romeil Sandhu Andrew L. Kung Prabhjot Mundi Joseph O. Deasy Allen Tannenbaum
author_facet	Yongxin Chen Filemon Dela Cruz Romeil Sandhu Andrew L. Kung Prabhjot Mundi Joseph O. Deasy Allen Tannenbaum
author_sort	Yongxin Chen
title	Pediatric Sarcoma Data Forms a Unique Cluster Measured via the Earth Mover’s Distance
title_short	Pediatric Sarcoma Data Forms a Unique Cluster Measured via the Earth Mover’s Distance
title_full	Pediatric Sarcoma Data Forms a Unique Cluster Measured via the Earth Mover’s Distance
title_fullStr	Pediatric Sarcoma Data Forms a Unique Cluster Measured via the Earth Mover’s Distance
title_full_unstemmed	Pediatric Sarcoma Data Forms a Unique Cluster Measured via the Earth Mover’s Distance
title_sort	pediatric sarcoma data forms a unique cluster measured via the earth mover’s distance
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/a79b7a3d0c4e4c8f9950c14e91f13336
work_keys_str_mv	AT yongxinchen pediatricsarcomadataformsauniqueclustermeasuredviatheearthmoversdistance AT filemondelacruz pediatricsarcomadataformsauniqueclustermeasuredviatheearthmoversdistance AT romeilsandhu pediatricsarcomadataformsauniqueclustermeasuredviatheearthmoversdistance AT andrewlkung pediatricsarcomadataformsauniqueclustermeasuredviatheearthmoversdistance AT prabhjotmundi pediatricsarcomadataformsauniqueclustermeasuredviatheearthmoversdistance AT josephodeasy pediatricsarcomadataformsauniqueclustermeasuredviatheearthmoversdistance AT allentannenbaum pediatricsarcomadataformsauniqueclustermeasuredviatheearthmoversdistance
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Pediatric Sarcoma Data Forms a Unique Cluster Measured via the Earth Mover’s Distance

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