Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations

Eric Jorgenson and Hélène Choquet et al. find that northwestern European genetic ancestry is associated with increased risk of cutaneous squamous cell carcinoma (cSCC) in non-Hispanic whites, and more so in Hispanic/Latinos of the US. The ancestry effect is largely, but not entirely explained by gen...

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Autores principales:	Eric Jorgenson, Hélène Choquet, Jie Yin, Thomas J. Hoffmann, Yambazi Banda, Mark N. Kvale, Neil Risch, Catherine Schaefer, Maryam M. Asgari
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/a79cd18f5bf6479896536dc7deec0a5d
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spelling	oai:doaj.org-article:a79cd18f5bf6479896536dc7deec0a5d2021-12-02T13:56:15ZGenetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations10.1038/s42003-020-01461-82399-3642https://doaj.org/article/a79cd18f5bf6479896536dc7deec0a5d2020-12-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01461-8https://doaj.org/toc/2399-3642Eric Jorgenson and Hélène Choquet et al. find that northwestern European genetic ancestry is associated with increased risk of cutaneous squamous cell carcinoma (cSCC) in non-Hispanic whites, and more so in Hispanic/Latinos of the US. The ancestry effect is largely, but not entirely explained by genetic determinants of skin pigmentation in both populations.Eric JorgensonHélène ChoquetJie YinThomas J. HoffmannYambazi BandaMark N. KvaleNeil RischCatherine SchaeferMaryam M. AsgariNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 3, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Eric Jorgenson Hélène Choquet Jie Yin Thomas J. Hoffmann Yambazi Banda Mark N. Kvale Neil Risch Catherine Schaefer Maryam M. Asgari Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations
description	Eric Jorgenson and Hélène Choquet et al. find that northwestern European genetic ancestry is associated with increased risk of cutaneous squamous cell carcinoma (cSCC) in non-Hispanic whites, and more so in Hispanic/Latinos of the US. The ancestry effect is largely, but not entirely explained by genetic determinants of skin pigmentation in both populations.
format	article
author	Eric Jorgenson Hélène Choquet Jie Yin Thomas J. Hoffmann Yambazi Banda Mark N. Kvale Neil Risch Catherine Schaefer Maryam M. Asgari
author_facet	Eric Jorgenson Hélène Choquet Jie Yin Thomas J. Hoffmann Yambazi Banda Mark N. Kvale Neil Risch Catherine Schaefer Maryam M. Asgari
author_sort	Eric Jorgenson
title	Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations
title_short	Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations
title_full	Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations
title_fullStr	Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations
title_full_unstemmed	Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations
title_sort	genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in hispanic/latino and non-hispanic white populations
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a79cd18f5bf6479896536dc7deec0a5d
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Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations

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