Requirement of heterogeneous nuclear ribonucleoprotein C for BRCA gene expression and homologous recombination.

Requirement of heterogeneous nuclear ribonucleoprotein C for BRCA gene expression and homologous recombination.

<h4>Background</h4>Heterogeneous nuclear ribonucleoprotein C1/C2 (hnRNP C) is a core component of 40S ribonucleoprotein particles that bind pre-mRNAs and influence their processing, stability and export. Breast cancer tumor suppressors BRCA1, BRCA2 and PALB2 form a complex and play key r...

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Autores principales: Rachel W Anantha, Allen L Alcivar, Jianglin Ma, Hong Cai, Srilatha Simhadri, Jernej Ule, Julian König, Bing Xia
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a79da91d1a434b5790e0990a90671af6
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