PPAR-γ regulates carnitine homeostasis and mitochondrial function in a lamb model of increased pulmonary blood flow.
<h4>Objective</h4>Carnitine homeostasis is disrupted in lambs with endothelial dysfunction secondary to increased pulmonary blood flow (Shunt). Our recent studies have also indicated that the disruption in carnitine homeostasis correlates with a decrease in PPAR-γ expression in Shunt lam...
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Autores principales: | Shruti Sharma, Xutong Sun, Ruslan Rafikov, Sanjiv Kumar, Yali Hou, Peter E Oishi, Sanjeev A Datar, Gary Raff, Jeffrey R Fineman, Stephen M Black |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/a79e930a075b47b2a8661612db632d90 |
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