PPAR-γ regulates carnitine homeostasis and mitochondrial function in a lamb model of increased pulmonary blood flow.

<h4>Objective</h4>Carnitine homeostasis is disrupted in lambs with endothelial dysfunction secondary to increased pulmonary blood flow (Shunt). Our recent studies have also indicated that the disruption in carnitine homeostasis correlates with a decrease in PPAR-γ expression in Shunt lam...

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Autores principales: Shruti Sharma, Xutong Sun, Ruslan Rafikov, Sanjiv Kumar, Yali Hou, Peter E Oishi, Sanjeev A Datar, Gary Raff, Jeffrey R Fineman, Stephen M Black
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/a79e930a075b47b2a8661612db632d90
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