HDAC1-Dependent Repression of Markers of Hepatocytes and P21 Is Involved in Development of Pediatric Liver CancerSummary

HDAC1-Dependent Repression of Markers of Hepatocytes and P21 Is Involved in Development of Pediatric Liver CancerSummary

Background & Aims: Epigenetic regulation of gene expression plays a critical role in the development of liver cancer; however, the molecular mechanisms of epigenetic-driven liver cancers are not well understood. The aims of this study were to examine molecular mechanisms that cause the dedif...

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Bibliographic Details
Main Authors: Maria Rivas, Michael E. Johnston, II, Ruhi Gulati, Meenasri Kumbaji, Talita Ferreira Margues Aguiar, Lubov Timchenko, Ana Krepischi, Soona Shin, Alexander Bondoc, Gregory Tiao, James Geller, Nikolai Timchenko
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Hepatoblastoma
HDAC1
C/EBPα
Sp5
Epigenetic
Liver Cancer
Diseases of the digestive system. Gastroenterology
RC799-869
Online Access:https://doaj.org/article/a79ef3c66404472896ca72ae3a9c2d38
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https://doaj.org/article/a79ef3c66404472896ca72ae3a9c2d38

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