Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma
Sebaceous carcinomas (SeC) are cutaneous malignancies that sometimes metastasize and cause death. Here the authors perform whole-exome sequencing on 32 SeC and report distinct mutational classes that may explain cancer ontogeny and clinical outcome.
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Nature Portfolio
2018
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oai:doaj.org-article:a7a23b1126f944b2aad81a9029010a172021-12-02T16:50:10ZCell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma10.1038/s41467-018-04008-y2041-1723https://doaj.org/article/a7a23b1126f944b2aad81a9029010a172018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04008-yhttps://doaj.org/toc/2041-1723Sebaceous carcinomas (SeC) are cutaneous malignancies that sometimes metastasize and cause death. Here the authors perform whole-exome sequencing on 32 SeC and report distinct mutational classes that may explain cancer ontogeny and clinical outcome.Jeffrey P. NorthJustin GolovatoCharles J. VaskeJ. Zachary SanbornAndrew NguyenWei WuBenjamin GoodeMeredith SteversKevin McMullenBethany E. Perez WhiteEric A. CollissonMichele BloomerDavid A. SolomonStephen C. BenzRaymond J. ChoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Jeffrey P. North Justin Golovato Charles J. Vaske J. Zachary Sanborn Andrew Nguyen Wei Wu Benjamin Goode Meredith Stevers Kevin McMullen Bethany E. Perez White Eric A. Collisson Michele Bloomer David A. Solomon Stephen C. Benz Raymond J. Cho Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma |
| description |
Sebaceous carcinomas (SeC) are cutaneous malignancies that sometimes metastasize and cause death. Here the authors perform whole-exome sequencing on 32 SeC and report distinct mutational classes that may explain cancer ontogeny and clinical outcome. |
| format |
article |
| author |
Jeffrey P. North Justin Golovato Charles J. Vaske J. Zachary Sanborn Andrew Nguyen Wei Wu Benjamin Goode Meredith Stevers Kevin McMullen Bethany E. Perez White Eric A. Collisson Michele Bloomer David A. Solomon Stephen C. Benz Raymond J. Cho |
| author_facet |
Jeffrey P. North Justin Golovato Charles J. Vaske J. Zachary Sanborn Andrew Nguyen Wei Wu Benjamin Goode Meredith Stevers Kevin McMullen Bethany E. Perez White Eric A. Collisson Michele Bloomer David A. Solomon Stephen C. Benz Raymond J. Cho |
| author_sort |
Jeffrey P. North |
| title |
Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma |
| title_short |
Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma |
| title_full |
Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma |
| title_fullStr |
Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma |
| title_full_unstemmed |
Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma |
| title_sort |
cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/a7a23b1126f944b2aad81a9029010a17 |
| work_keys_str_mv |
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