Immune response elicited by DNA vaccination using Lactococcus lactis is modified by the production of surface exposed pathogenic protein.

Immune response elicited by DNA vaccination using Lactococcus lactis is modified by the production of surface exposed pathogenic protein.

In this study, we compared immune responses elicited by DNA immunization using Lactococcus lactis or L. lactis expressing the Staphylococcus aureus invasin Fibronectin Binding Protein A (FnBPA) at its surface. Both strains carried pValac:BLG, a plasmid containing the cDNA of Beta-Lactoglobulin (BLG)...

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Autores principales: Daniela Pontes, Marcela Azevedo, Silvia Innocentin, Sébastien Blugeon, François Lefévre, Vasco Azevedo, Anderson Miyoshi, Pascal Courtin, Marie-Pierre Chapot-Chartier, Philippe Langella, Jean-Marc Chatel
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a7a3791ab4f94f0a9de246f31b362d37
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