A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium
Iron is an essential nutrient but, in high concentrations, it is also toxic to cells. Here, Slavic et al. identify an iron transporter in malaria parasites that plays a major role in iron detoxification and is required for the parasite’s normal development.
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Nature Portfolio
2016
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oai:doaj.org-article:a7ab0e1ec823404b880357bf65649df62021-12-02T14:40:13ZA vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium10.1038/ncomms104032041-1723https://doaj.org/article/a7ab0e1ec823404b880357bf65649df62016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10403https://doaj.org/toc/2041-1723Iron is an essential nutrient but, in high concentrations, it is also toxic to cells. Here, Slavic et al. identify an iron transporter in malaria parasites that plays a major role in iron detoxification and is required for the parasite’s normal development.Ksenija SlavicSanjeev KrishnaAparajita LahreeGuillaume BouyerKirsten K. HansonIset VeraJon K. PittmanHenry M. StainesMaria M. MotaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016) |
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Science Q Ksenija Slavic Sanjeev Krishna Aparajita Lahree Guillaume Bouyer Kirsten K. Hanson Iset Vera Jon K. Pittman Henry M. Staines Maria M. Mota A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium |
description |
Iron is an essential nutrient but, in high concentrations, it is also toxic to cells. Here, Slavic et al. identify an iron transporter in malaria parasites that plays a major role in iron detoxification and is required for the parasite’s normal development. |
format |
article |
author |
Ksenija Slavic Sanjeev Krishna Aparajita Lahree Guillaume Bouyer Kirsten K. Hanson Iset Vera Jon K. Pittman Henry M. Staines Maria M. Mota |
author_facet |
Ksenija Slavic Sanjeev Krishna Aparajita Lahree Guillaume Bouyer Kirsten K. Hanson Iset Vera Jon K. Pittman Henry M. Staines Maria M. Mota |
author_sort |
Ksenija Slavic |
title |
A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium |
title_short |
A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium |
title_full |
A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium |
title_fullStr |
A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium |
title_full_unstemmed |
A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium |
title_sort |
vacuolar iron-transporter homologue acts as a detoxifier in plasmodium |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/a7ab0e1ec823404b880357bf65649df6 |
work_keys_str_mv |
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1718390373782388736 |