A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium

Iron is an essential nutrient but, in high concentrations, it is also toxic to cells. Here, Slavic et al. identify an iron transporter in malaria parasites that plays a major role in iron detoxification and is required for the parasite’s normal development.

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Autores principales: Ksenija Slavic, Sanjeev Krishna, Aparajita Lahree, Guillaume Bouyer, Kirsten K. Hanson, Iset Vera, Jon K. Pittman, Henry M. Staines, Maria M. Mota
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/a7ab0e1ec823404b880357bf65649df6
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spelling oai:doaj.org-article:a7ab0e1ec823404b880357bf65649df62021-12-02T14:40:13ZA vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium10.1038/ncomms104032041-1723https://doaj.org/article/a7ab0e1ec823404b880357bf65649df62016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10403https://doaj.org/toc/2041-1723Iron is an essential nutrient but, in high concentrations, it is also toxic to cells. Here, Slavic et al. identify an iron transporter in malaria parasites that plays a major role in iron detoxification and is required for the parasite’s normal development.Ksenija SlavicSanjeev KrishnaAparajita LahreeGuillaume BouyerKirsten K. HansonIset VeraJon K. PittmanHenry M. StainesMaria M. MotaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ksenija Slavic
Sanjeev Krishna
Aparajita Lahree
Guillaume Bouyer
Kirsten K. Hanson
Iset Vera
Jon K. Pittman
Henry M. Staines
Maria M. Mota
A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium
description Iron is an essential nutrient but, in high concentrations, it is also toxic to cells. Here, Slavic et al. identify an iron transporter in malaria parasites that plays a major role in iron detoxification and is required for the parasite’s normal development.
format article
author Ksenija Slavic
Sanjeev Krishna
Aparajita Lahree
Guillaume Bouyer
Kirsten K. Hanson
Iset Vera
Jon K. Pittman
Henry M. Staines
Maria M. Mota
author_facet Ksenija Slavic
Sanjeev Krishna
Aparajita Lahree
Guillaume Bouyer
Kirsten K. Hanson
Iset Vera
Jon K. Pittman
Henry M. Staines
Maria M. Mota
author_sort Ksenija Slavic
title A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium
title_short A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium
title_full A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium
title_fullStr A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium
title_full_unstemmed A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium
title_sort vacuolar iron-transporter homologue acts as a detoxifier in plasmodium
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/a7ab0e1ec823404b880357bf65649df6
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