Enantioselectivity of Chiral Derivatives of Xanthones in Virulence Effects of Resistant Bacteria

Antimicrobial peptides are one of the lines of defense produced by several hosts in response to bacterial infections. Inspired by them and recent discoveries of xanthones as bacterial efflux pump inhibitors, chiral amides with a xanthone scaffold were planned to be potential antimicrobial adjuvants....

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Main Authors: Fernando Durães, Sara Cravo, Joana Freitas-Silva, Nikoletta Szemerédi, Paulo Martins-da-Costa, Eugénia Pinto, Maria Elizabeth Tiritan, Gabriella Spengler, Carla Fernandes, Emília Sousa, Madalena Pinto
Format: article
Language:EN
Published: MDPI AG 2021
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R
Online Access:https://doaj.org/article/a7abe5ef10784e8cbb60ef22a03b49a7
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