Initial study on removing cellular residues from hydrostatic high-pressure treated allogeneic tissue using ultrasound

Hydrostatic high-pressure technology (HHD) devitalizes tissue quickly and gently, without negatively affecting the structural properties. HHD-treated tissues must be cleaned from devitalized cells. A partially automated, gentle, reproducible and timesaving rinsing test setup utilizing ultrasound is...

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Autores principales:	Drobek Christoph, Waletzko Janine, Dau Michael, Frerich Bernhard, Weißmann Volker, Schwerdt Daniela, Seehafer Stefan, Mau Robert, Seitz Hermann, Jonitz-Heincke Anika, Bader Rainer
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2020
Materias:	hhd allograft cell residue decellularization rinsing device ultrasound test setup bone tissue Medicine R
Acceso en línea:	https://doaj.org/article/a7ac3c2c240642d2884f8626a9db0053
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spelling	oai:doaj.org-article:a7ac3c2c240642d2884f8626a9db00532021-12-05T14:10:42ZInitial study on removing cellular residues from hydrostatic high-pressure treated allogeneic tissue using ultrasound2364-550410.1515/cdbme-2020-3045https://doaj.org/article/a7ac3c2c240642d2884f8626a9db00532020-09-01T00:00:00Zhttps://doi.org/10.1515/cdbme-2020-3045https://doaj.org/toc/2364-5504Hydrostatic high-pressure technology (HHD) devitalizes tissue quickly and gently, without negatively affecting the structural properties. HHD-treated tissues must be cleaned from devitalized cells. A partially automated, gentle, reproducible and timesaving rinsing test setup utilizing ultrasound is demonstrated in this study. The test setup is used to clean HHD-treated bone allografts of tissue residues and prevent microbiological contamination. A rinsing procedure is investigated. Residual DNA content determination is utilized to analyze cleaned bone allograft tissue for rinsing procedure evaluation.Drobek ChristophWaletzko JanineDau MichaelFrerich BernhardWeißmann VolkerSchwerdt DanielaSeehafer StefanMau RobertSeitz HermannJonitz-Heincke AnikaBader RainerDe Gruyterarticlehhdallograftcell residuedecellularizationrinsing deviceultrasoundtest setupbone tissueMedicineRENCurrent Directions in Biomedical Engineering, Vol 6, Iss 3, Pp 176-179 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	hhd allograft cell residue decellularization rinsing device ultrasound test setup bone tissue Medicine R
spellingShingle	hhd allograft cell residue decellularization rinsing device ultrasound test setup bone tissue Medicine R Drobek Christoph Waletzko Janine Dau Michael Frerich Bernhard Weißmann Volker Schwerdt Daniela Seehafer Stefan Mau Robert Seitz Hermann Jonitz-Heincke Anika Bader Rainer Initial study on removing cellular residues from hydrostatic high-pressure treated allogeneic tissue using ultrasound
description	Hydrostatic high-pressure technology (HHD) devitalizes tissue quickly and gently, without negatively affecting the structural properties. HHD-treated tissues must be cleaned from devitalized cells. A partially automated, gentle, reproducible and timesaving rinsing test setup utilizing ultrasound is demonstrated in this study. The test setup is used to clean HHD-treated bone allografts of tissue residues and prevent microbiological contamination. A rinsing procedure is investigated. Residual DNA content determination is utilized to analyze cleaned bone allograft tissue for rinsing procedure evaluation.
format	article
author	Drobek Christoph Waletzko Janine Dau Michael Frerich Bernhard Weißmann Volker Schwerdt Daniela Seehafer Stefan Mau Robert Seitz Hermann Jonitz-Heincke Anika Bader Rainer
author_facet	Drobek Christoph Waletzko Janine Dau Michael Frerich Bernhard Weißmann Volker Schwerdt Daniela Seehafer Stefan Mau Robert Seitz Hermann Jonitz-Heincke Anika Bader Rainer
author_sort	Drobek Christoph
title	Initial study on removing cellular residues from hydrostatic high-pressure treated allogeneic tissue using ultrasound
title_short	Initial study on removing cellular residues from hydrostatic high-pressure treated allogeneic tissue using ultrasound
title_full	Initial study on removing cellular residues from hydrostatic high-pressure treated allogeneic tissue using ultrasound
title_fullStr	Initial study on removing cellular residues from hydrostatic high-pressure treated allogeneic tissue using ultrasound
title_full_unstemmed	Initial study on removing cellular residues from hydrostatic high-pressure treated allogeneic tissue using ultrasound
title_sort	initial study on removing cellular residues from hydrostatic high-pressure treated allogeneic tissue using ultrasound
publisher	De Gruyter
publishDate	2020
url	https://doaj.org/article/a7ac3c2c240642d2884f8626a9db0053
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Initial study on removing cellular residues from hydrostatic high-pressure treated allogeneic tissue using ultrasound

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