Genetic architecture of human plasma lipidome and its link to cardiovascular disease

Cardiovascular diseases (CVD) are associated with plasma lipid levels. Here, Tabassum et al. perform genome-wide association studies for lipidomic profiles with 141 (non-standard) lipid species which highlights shared genetic loci with CVD and that traditional lipids have low genetic correlation wit...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Rubina Tabassum, Joel T. Rämö, Pietari Ripatti, Jukka T. Koskela, Mitja Kurki, Juha Karjalainen, Priit Palta, Shabbeer Hassan, Javier Nunez-Fontarnau, Tuomo T. J. Kiiskinen, Sanni Söderlund, Niina Matikainen, Mathias J. Gerl, Michal A. Surma, Christian Klose, Nathan O. Stitziel, Hannele Laivuori, Aki S. Havulinna, Susan K. Service, Veikko Salomaa, Matti Pirinen, FinnGen Project, Matti Jauhiainen, Mark J. Daly, Nelson B. Freimer, Aarno Palotie, Marja-Riitta Taskinen, Kai Simons, Samuli Ripatti
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a7b6a56d3eec433f97120fae91d896c5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a7b6a56d3eec433f97120fae91d896c5
record_format	dspace
spelling	oai:doaj.org-article:a7b6a56d3eec433f97120fae91d896c52021-12-02T15:35:30ZGenetic architecture of human plasma lipidome and its link to cardiovascular disease10.1038/s41467-019-11954-82041-1723https://doaj.org/article/a7b6a56d3eec433f97120fae91d896c52019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11954-8https://doaj.org/toc/2041-1723Cardiovascular diseases (CVD) are associated with plasma lipid levels. Here, Tabassum et al. perform genome-wide association studies for lipidomic profiles with 141 (non-standard) lipid species which highlights shared genetic loci with CVD and that traditional lipids have low genetic correlation with other lipids.Rubina TabassumJoel T. RämöPietari RipattiJukka T. KoskelaMitja KurkiJuha KarjalainenPriit PaltaShabbeer HassanJavier Nunez-FontarnauTuomo T. J. KiiskinenSanni SöderlundNiina MatikainenMathias J. GerlMichal A. SurmaChristian KloseNathan O. StitzielHannele LaivuoriAki S. HavulinnaSusan K. ServiceVeikko SalomaaMatti PirinenFinnGen ProjectMatti JauhiainenMark J. DalyNelson B. FreimerAarno PalotieMarja-Riitta TaskinenKai SimonsSamuli RipattiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rubina Tabassum Joel T. Rämö Pietari Ripatti Jukka T. Koskela Mitja Kurki Juha Karjalainen Priit Palta Shabbeer Hassan Javier Nunez-Fontarnau Tuomo T. J. Kiiskinen Sanni Söderlund Niina Matikainen Mathias J. Gerl Michal A. Surma Christian Klose Nathan O. Stitziel Hannele Laivuori Aki S. Havulinna Susan K. Service Veikko Salomaa Matti Pirinen FinnGen Project Matti Jauhiainen Mark J. Daly Nelson B. Freimer Aarno Palotie Marja-Riitta Taskinen Kai Simons Samuli Ripatti Genetic architecture of human plasma lipidome and its link to cardiovascular disease
description	Cardiovascular diseases (CVD) are associated with plasma lipid levels. Here, Tabassum et al. perform genome-wide association studies for lipidomic profiles with 141 (non-standard) lipid species which highlights shared genetic loci with CVD and that traditional lipids have low genetic correlation with other lipids.
format	article
author	Rubina Tabassum Joel T. Rämö Pietari Ripatti Jukka T. Koskela Mitja Kurki Juha Karjalainen Priit Palta Shabbeer Hassan Javier Nunez-Fontarnau Tuomo T. J. Kiiskinen Sanni Söderlund Niina Matikainen Mathias J. Gerl Michal A. Surma Christian Klose Nathan O. Stitziel Hannele Laivuori Aki S. Havulinna Susan K. Service Veikko Salomaa Matti Pirinen FinnGen Project Matti Jauhiainen Mark J. Daly Nelson B. Freimer Aarno Palotie Marja-Riitta Taskinen Kai Simons Samuli Ripatti
author_facet	Rubina Tabassum Joel T. Rämö Pietari Ripatti Jukka T. Koskela Mitja Kurki Juha Karjalainen Priit Palta Shabbeer Hassan Javier Nunez-Fontarnau Tuomo T. J. Kiiskinen Sanni Söderlund Niina Matikainen Mathias J. Gerl Michal A. Surma Christian Klose Nathan O. Stitziel Hannele Laivuori Aki S. Havulinna Susan K. Service Veikko Salomaa Matti Pirinen FinnGen Project Matti Jauhiainen Mark J. Daly Nelson B. Freimer Aarno Palotie Marja-Riitta Taskinen Kai Simons Samuli Ripatti
author_sort	Rubina Tabassum
title	Genetic architecture of human plasma lipidome and its link to cardiovascular disease
title_short	Genetic architecture of human plasma lipidome and its link to cardiovascular disease
title_full	Genetic architecture of human plasma lipidome and its link to cardiovascular disease
title_fullStr	Genetic architecture of human plasma lipidome and its link to cardiovascular disease
title_full_unstemmed	Genetic architecture of human plasma lipidome and its link to cardiovascular disease
title_sort	genetic architecture of human plasma lipidome and its link to cardiovascular disease
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/a7b6a56d3eec433f97120fae91d896c5
work_keys_str_mv	AT rubinatabassum geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT joeltramo geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT pietariripatti geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT jukkatkoskela geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT mitjakurki geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT juhakarjalainen geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT priitpalta geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT shabbeerhassan geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT javiernunezfontarnau geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT tuomotjkiiskinen geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT sannisoderlund geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT niinamatikainen geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT mathiasjgerl geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT michalasurma geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT christianklose geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT nathanostitziel geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT hannelelaivuori geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT akishavulinna geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT susankservice geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT veikkosalomaa geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT mattipirinen geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT finngenproject geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT mattijauhiainen geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT markjdaly geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT nelsonbfreimer geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT aarnopalotie geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT marjariittataskinen geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT kaisimons geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease AT samuliripatti geneticarchitectureofhumanplasmalipidomeanditslinktocardiovasculardisease
_version_	1718386552664489984

Genetic architecture of human plasma lipidome and its link to cardiovascular disease

Ejemplares similares