Cardiovascular Pathophysiology in Chronic Kidney Disease: Opportunities to Transition from Disease to Health

Background: Chronic kidney disease (CKD) is common, and is associated with a high burden of cardiovascular disease. This cardiovascular risk is incompletely explained by traditional risk factors, calling attention to a need to better understand the pathways in CKD contributing to adverse cardiovascu...

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Autores principales:	Matthew I. Tomey, Jonathan A. Winston
Formato:	article
Lenguaje:	EN
Publicado:	Ubiquity Press 2014
Materias:	cardiorenal syndrome cardiovascular disease chronic kidney disease renocardiac syndrome Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/a7b95be07c9e419281b5b8438ff390ae
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spelling	oai:doaj.org-article:a7b95be07c9e419281b5b8438ff390ae2021-12-02T02:48:13ZCardiovascular Pathophysiology in Chronic Kidney Disease: Opportunities to Transition from Disease to Health2214-999610.1016/j.aogh.2013.12.007https://doaj.org/article/a7b95be07c9e419281b5b8438ff390ae2014-04-01T00:00:00Zhttps://annalsofglobalhealth.org/articles/83https://doaj.org/toc/2214-9996Background: Chronic kidney disease (CKD) is common, and is associated with a high burden of cardiovascular disease. This cardiovascular risk is incompletely explained by traditional risk factors, calling attention to a need to better understand the pathways in CKD contributing to adverse cardiovascular outcomes. Findings: Pathophysiological derangements associated with CKD, including disordered sodium, potassium, and water homeostasis, renin-angiotensin-aldosterone and sympathetic activity, anemia, bone and mineral metabolism, uremia, and toxin accumulation may contribute directly to progression of cardiovascular disease and adverse outcomes. Conclusion: Improving cardiovascular health in patients with CKD requires improved understanding of renocardiac pathophysiology. Ultimately, the most successful strategy may be prevention of incident CKD itself.Matthew I. TomeyJonathan A. WinstonUbiquity Pressarticlecardiorenal syndromecardiovascular diseasechronic kidney diseaserenocardiac syndromeInfectious and parasitic diseasesRC109-216Public aspects of medicineRA1-1270ENAnnals of Global Health, Vol 80, Iss 1, Pp 69-79 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	cardiorenal syndrome cardiovascular disease chronic kidney disease renocardiac syndrome Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270
spellingShingle	cardiorenal syndrome cardiovascular disease chronic kidney disease renocardiac syndrome Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270 Matthew I. Tomey Jonathan A. Winston Cardiovascular Pathophysiology in Chronic Kidney Disease: Opportunities to Transition from Disease to Health
description	Background: Chronic kidney disease (CKD) is common, and is associated with a high burden of cardiovascular disease. This cardiovascular risk is incompletely explained by traditional risk factors, calling attention to a need to better understand the pathways in CKD contributing to adverse cardiovascular outcomes. Findings: Pathophysiological derangements associated with CKD, including disordered sodium, potassium, and water homeostasis, renin-angiotensin-aldosterone and sympathetic activity, anemia, bone and mineral metabolism, uremia, and toxin accumulation may contribute directly to progression of cardiovascular disease and adverse outcomes. Conclusion: Improving cardiovascular health in patients with CKD requires improved understanding of renocardiac pathophysiology. Ultimately, the most successful strategy may be prevention of incident CKD itself.
format	article
author	Matthew I. Tomey Jonathan A. Winston
author_facet	Matthew I. Tomey Jonathan A. Winston
author_sort	Matthew I. Tomey
title	Cardiovascular Pathophysiology in Chronic Kidney Disease: Opportunities to Transition from Disease to Health
title_short	Cardiovascular Pathophysiology in Chronic Kidney Disease: Opportunities to Transition from Disease to Health
title_full	Cardiovascular Pathophysiology in Chronic Kidney Disease: Opportunities to Transition from Disease to Health
title_fullStr	Cardiovascular Pathophysiology in Chronic Kidney Disease: Opportunities to Transition from Disease to Health
title_full_unstemmed	Cardiovascular Pathophysiology in Chronic Kidney Disease: Opportunities to Transition from Disease to Health
title_sort	cardiovascular pathophysiology in chronic kidney disease: opportunities to transition from disease to health
publisher	Ubiquity Press
publishDate	2014
url	https://doaj.org/article/a7b95be07c9e419281b5b8438ff390ae
work_keys_str_mv	AT matthewitomey cardiovascularpathophysiologyinchronickidneydiseaseopportunitiestotransitionfromdiseasetohealth AT jonathanawinston cardiovascularpathophysiologyinchronickidneydiseaseopportunitiestotransitionfromdiseasetohealth
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Cardiovascular Pathophysiology in Chronic Kidney Disease: Opportunities to Transition from Disease to Health

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