A Case Report of Neonatal Pemphigus Vulgaris
Background and Objectives: Pemphigus vulgaris (PV) is a chronic, rare mucocutaneous autoimmune bullous disease characterized by flaccid blisters and or pustules, with secondary erosions of the mucous membranes or skin. PV threatens the patient life by forming splits within the epidermis, accompanied...
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| Autores principales: | , , |
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| Formato: | article |
| Lenguaje: | FA |
| Publicado: |
Qom University of Medical Sciences
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/a7d05d5566214c1290a09c3189d9816a |
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| Sumario: | Background and Objectives: Pemphigus vulgaris (PV) is a chronic, rare mucocutaneous autoimmune bullous disease characterized by flaccid blisters and or pustules, with secondary erosions of the mucous membranes or skin. PV threatens the patient life by forming splits within the epidermis, accompanied by acantholysis (separating keratinocytes from each other).
Case Presentation: Our case is a term female neonate with PV, born of a 31-year-old mother. On initial examination by a pediatrician, several thin-walled flaccid blisters and burst blisters accompanied with open sores were observed on the skin of hands, feet, face, and mucosa of the oral cavity, tongue, and throat. A positive Nikolskychr('39')s sign confirmed her involvement with the disease. |
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