A Case Report of Neonatal Pemphigus Vulgaris

Background and Objectives: Pemphigus vulgaris (PV) is a chronic, rare mucocutaneous autoimmune bullous disease characterized by flaccid blisters and or pustules, with secondary erosions of the mucous membranes or skin. PV threatens the patient life by forming splits within the epidermis, accompanied...

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Autores principales: Marzieh Alipour, Khalil Khashei Varnamkhasti, Marzieh Eslami Moghaddam
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Publicado: Qom University of Medical Sciences 2021
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spelling oai:doaj.org-article:a7d05d5566214c1290a09c3189d9816a2021-12-05T11:40:13ZA Case Report of Neonatal Pemphigus Vulgaris1735-77992008-1375https://doaj.org/article/a7d05d5566214c1290a09c3189d9816a2021-07-01T00:00:00Zhttp://journal.muq.ac.ir/article-1-3125-en.htmlhttps://doaj.org/toc/1735-7799https://doaj.org/toc/2008-1375Background and Objectives: Pemphigus vulgaris (PV) is a chronic, rare mucocutaneous autoimmune bullous disease characterized by flaccid blisters and or pustules, with secondary erosions of the mucous membranes or skin. PV threatens the patient life by forming splits within the epidermis, accompanied by acantholysis (separating keratinocytes from each other). Case Presentation: Our case is a term female neonate with PV, born of a 31-year-old mother. On initial examination by a pediatrician, several thin-walled flaccid blisters and burst blisters accompanied with open sores were observed on the skin of hands, feet, face, and mucosa of the oral cavity, tongue, and throat. A positive Nikolskychr('39')s sign confirmed her involvement with the disease.Marzieh AlipourKhalil Khashei VarnamkhastiMarzieh Eslami MoghaddamQom University of Medical Sciencesarticlepemphigus vulgarispemphigusautoimmunemucocutaneousMedicine (General)R5-920FAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, Vol 15, Iss 4, Pp 306-311 (2021)
institution DOAJ
collection DOAJ
language FA
topic pemphigus vulgaris
pemphigus
autoimmune
mucocutaneous
Medicine (General)
R5-920
spellingShingle pemphigus vulgaris
pemphigus
autoimmune
mucocutaneous
Medicine (General)
R5-920
Marzieh Alipour
Khalil Khashei Varnamkhasti
Marzieh Eslami Moghaddam
A Case Report of Neonatal Pemphigus Vulgaris
description Background and Objectives: Pemphigus vulgaris (PV) is a chronic, rare mucocutaneous autoimmune bullous disease characterized by flaccid blisters and or pustules, with secondary erosions of the mucous membranes or skin. PV threatens the patient life by forming splits within the epidermis, accompanied by acantholysis (separating keratinocytes from each other). Case Presentation: Our case is a term female neonate with PV, born of a 31-year-old mother. On initial examination by a pediatrician, several thin-walled flaccid blisters and burst blisters accompanied with open sores were observed on the skin of hands, feet, face, and mucosa of the oral cavity, tongue, and throat. A positive Nikolskychr('39')s sign confirmed her involvement with the disease.
format article
author Marzieh Alipour
Khalil Khashei Varnamkhasti
Marzieh Eslami Moghaddam
author_facet Marzieh Alipour
Khalil Khashei Varnamkhasti
Marzieh Eslami Moghaddam
author_sort Marzieh Alipour
title A Case Report of Neonatal Pemphigus Vulgaris
title_short A Case Report of Neonatal Pemphigus Vulgaris
title_full A Case Report of Neonatal Pemphigus Vulgaris
title_fullStr A Case Report of Neonatal Pemphigus Vulgaris
title_full_unstemmed A Case Report of Neonatal Pemphigus Vulgaris
title_sort case report of neonatal pemphigus vulgaris
publisher Qom University of Medical Sciences
publishDate 2021
url https://doaj.org/article/a7d05d5566214c1290a09c3189d9816a
work_keys_str_mv AT marziehalipour acasereportofneonatalpemphigusvulgaris
AT khalilkhasheivarnamkhasti acasereportofneonatalpemphigusvulgaris
AT marzieheslamimoghaddam acasereportofneonatalpemphigusvulgaris
AT marziehalipour casereportofneonatalpemphigusvulgaris
AT khalilkhasheivarnamkhasti casereportofneonatalpemphigusvulgaris
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