High-fat diet induces apoptosis of hypothalamic neurons.
Consumption of dietary fats is amongst the most important environmental factors leading to obesity. In rodents, the consumption of fat-rich diets blunts leptin and insulin anorexigenic signaling in the hypothalamus by a mechanism dependent on the in situ activation of inflammation. Since inflammator...
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Auteurs principaux: | Juliana C Moraes, Andressa Coope, Joseane Morari, Dennys E Cintra, Erika A Roman, José R Pauli, Talita Romanatto, José B Carvalheira, Alexandre L R Oliveira, Mario J Saad, Licio A Velloso |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2009
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Accès en ligne: | https://doaj.org/article/a7d0e63a092644f5bc26ec40e48366f8 |
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