High-fat diet induces apoptosis of hypothalamic neurons.

High-fat diet induces apoptosis of hypothalamic neurons.

Consumption of dietary fats is amongst the most important environmental factors leading to obesity. In rodents, the consumption of fat-rich diets blunts leptin and insulin anorexigenic signaling in the hypothalamus by a mechanism dependent on the in situ activation of inflammation. Since inflammator...

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Autores principales: Juliana C Moraes, Andressa Coope, Joseane Morari, Dennys E Cintra, Erika A Roman, José R Pauli, Talita Romanatto, José B Carvalheira, Alexandre L R Oliveira, Mario J Saad, Licio A Velloso
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a7d0e63a092644f5bc26ec40e48366f8
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