Establishment of appropriate glaucoma models using dexamethasone or TGFβ2 treated three-dimension (3D) cultured human trabecular meshwork (HTM) cells

Abstract To establish appropriate ex vivo models for a glaucomatous trabecular meshwork (TM), two-dimensional (2D) and three-dimensional (3D) cultures of human trabecular meshwork cells (HTM) were prepared in the presence of 250 nM dexamethasone (DEX) or 5 ng/mL TGFβ2, and characterized by the follo...

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Bibliographic Details
Main Authors: Megumi Watanabe, Yosuke Ida, Hiroshi Ohguro, Chiaki Ota, Fumihito Hikage
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
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Q
Online Access:https://doaj.org/article/a7ddc0f364e746eaaef259bff88b39bc
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