Endothelial dysfunction in development of cerebrovascular disorders in patients with diabetes mellitus

Endothelial dysfunction and aberrations of haemostasis play an important part in development of cerebrovascular disorders in patientswith diabetes mellitus. Such factors as hyper- and hypoglycemia, hyperinsulinism, insulin resistance and excessive weight affect progressionof microcirculation deficie...

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Main Authors: Evgenia Pavlovna Kosobyan, Ivona Renata Yarek-Martynova, Mikhail Yur'evich Martynov, Alla Nikolaevna Yasamanova, Tatiana Ivanovna Kolesnikova
Format: article
Language:EN
RU
Published: Endocrinology Research Centre 2012
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Online Access:https://doaj.org/article/a7dea90d469a4727a349b908d7743d8c
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Summary:Endothelial dysfunction and aberrations of haemostasis play an important part in development of cerebrovascular disorders in patientswith diabetes mellitus. Such factors as hyper- and hypoglycemia, hyperinsulinism, insulin resistance and excessive weight affect progressionof microcirculation deficiency and cerebral ischemia. Transcranial Doppler ultrasound examination is useful as a noninvasivemethod of hemodynamic assessment.