Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer
Current preclinical models to investigate human HR + breast cancer progression and response to immunotherapy in vivo are limited. Here, the authors demonstrate that mammary tumours driven by a synthetic progestin combined with an oral carcinogen recapitulate several immunobiological features of huma...
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2020
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/a7e37a6ac2cb4091b97dc956fd1c341a |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:a7e37a6ac2cb4091b97dc956fd1c341a |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:a7e37a6ac2cb4091b97dc956fd1c341a2021-12-02T16:14:05ZImmunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer10.1038/s41467-020-17644-02041-1723https://doaj.org/article/a7e37a6ac2cb4091b97dc956fd1c341a2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17644-0https://doaj.org/toc/2041-1723Current preclinical models to investigate human HR + breast cancer progression and response to immunotherapy in vivo are limited. Here, the authors demonstrate that mammary tumours driven by a synthetic progestin combined with an oral carcinogen recapitulate several immunobiological features of human HR + breast cancers.Aitziber BuquéNorma BloyMaria Perez-LanzónKristina IribarrenJuliette HumeauJonathan G. PolSarah LevesqueLaura MondragonTakahiro YamazakiAi SatoFernando ArandaSylvère DurandAlexandre BoissonnasJitka FucikovaLaura SenovillaDavid EnotMichal HenslerMargerie KremerGautier StollYang HuChiara MassaSilvia C. FormentiBarbara SeligerOlivier ElementoRadek SpisekFabrice AndréLaurence ZitvogelSuzette DelalogeGuido KroemerLorenzo GalluzziNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Aitziber Buqué Norma Bloy Maria Perez-Lanzón Kristina Iribarren Juliette Humeau Jonathan G. Pol Sarah Levesque Laura Mondragon Takahiro Yamazaki Ai Sato Fernando Aranda Sylvère Durand Alexandre Boissonnas Jitka Fucikova Laura Senovilla David Enot Michal Hensler Margerie Kremer Gautier Stoll Yang Hu Chiara Massa Silvia C. Formenti Barbara Seliger Olivier Elemento Radek Spisek Fabrice André Laurence Zitvogel Suzette Delaloge Guido Kroemer Lorenzo Galluzzi Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer |
| description |
Current preclinical models to investigate human HR + breast cancer progression and response to immunotherapy in vivo are limited. Here, the authors demonstrate that mammary tumours driven by a synthetic progestin combined with an oral carcinogen recapitulate several immunobiological features of human HR + breast cancers. |
| format |
article |
| author |
Aitziber Buqué Norma Bloy Maria Perez-Lanzón Kristina Iribarren Juliette Humeau Jonathan G. Pol Sarah Levesque Laura Mondragon Takahiro Yamazaki Ai Sato Fernando Aranda Sylvère Durand Alexandre Boissonnas Jitka Fucikova Laura Senovilla David Enot Michal Hensler Margerie Kremer Gautier Stoll Yang Hu Chiara Massa Silvia C. Formenti Barbara Seliger Olivier Elemento Radek Spisek Fabrice André Laurence Zitvogel Suzette Delaloge Guido Kroemer Lorenzo Galluzzi |
| author_facet |
Aitziber Buqué Norma Bloy Maria Perez-Lanzón Kristina Iribarren Juliette Humeau Jonathan G. Pol Sarah Levesque Laura Mondragon Takahiro Yamazaki Ai Sato Fernando Aranda Sylvère Durand Alexandre Boissonnas Jitka Fucikova Laura Senovilla David Enot Michal Hensler Margerie Kremer Gautier Stoll Yang Hu Chiara Massa Silvia C. Formenti Barbara Seliger Olivier Elemento Radek Spisek Fabrice André Laurence Zitvogel Suzette Delaloge Guido Kroemer Lorenzo Galluzzi |
| author_sort |
Aitziber Buqué |
| title |
Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer |
| title_short |
Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer |
| title_full |
Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer |
| title_fullStr |
Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer |
| title_full_unstemmed |
Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer |
| title_sort |
immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/a7e37a6ac2cb4091b97dc956fd1c341a |
| work_keys_str_mv |
AT aitziberbuque immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT normabloy immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT mariaperezlanzon immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT kristinairibarren immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT juliettehumeau immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT jonathangpol immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT sarahlevesque immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT lauramondragon immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT takahiroyamazaki immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT aisato immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT fernandoaranda immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT sylveredurand immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT alexandreboissonnas immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT jitkafucikova immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT laurasenovilla immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT davidenot immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT michalhensler immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT margeriekremer immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT gautierstoll immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT yanghu immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT chiaramassa immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT silviacformenti immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT barbaraseliger immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT olivierelemento immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT radekspisek immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT fabriceandre immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT laurencezitvogel immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT suzettedelaloge immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT guidokroemer immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer AT lorenzogalluzzi immunoprophylacticandimmunotherapeuticcontrolofhormonereceptorpositivebreastcancer |
| _version_ |
1718384368289841152 |