Toxoplasma gondii-induced activation of EGFR prevents autophagy protein-mediated killing of the parasite.

Toxoplasma gondii resides in an intracellular compartment (parasitophorous vacuole) that excludes transmembrane molecules required for endosome-lysosome recruitment. Thus, the parasite survives by avoiding lysosomal degradation. However, autophagy can re-route the parasitophorous vacuole to the lyso...

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Autores principales: Luis Muniz-Feliciano, Jennifer Van Grol, Jose-Andres C Portillo, Lloyd Liew, Bing Liu, Cathleen R Carlin, Vern B Carruthers, Stephen Matthews, Carlos S Subauste
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/a7e60ba2904940118547708938ad7a9e
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