Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia
Minfeng Cheng,* Huaying Gu,* Liangrong Zheng, Houliang Wang, Zhiyong Zhong, Shenglin Wen Department of Psychiatry, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China *These authors contributed equally to this work Abstract: Here, we repor...
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Dove Medical Press
2016
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oai:doaj.org-article:a7ef09e2ad1049538b8fff79fb4ba05b2021-12-02T00:37:26ZNeuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia1178-2021https://doaj.org/article/a7ef09e2ad1049538b8fff79fb4ba05b2016-03-01T00:00:00Zhttps://www.dovepress.com/neuroleptic-malignant-syndrome-and-subsequent-clozapine-withdrawal-eff-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Minfeng Cheng,* Huaying Gu,* Liangrong Zheng, Houliang Wang, Zhiyong Zhong, Shenglin Wen Department of Psychiatry, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China *These authors contributed equally to this work Abstract: Here, we report a female patient developing neuroleptic malignant syndrome following the use of a combination of clozapine and haloperidol. Subsequently, the patient presented withdrawal effects after an abrupt discontinuation of clozapine. Psychiatrists not aware of possible clozapine-withdrawal effects may misdiagnose as a part of the primary mental illness or as the initial symptoms worsening, if unrecognized. Keywords: clozapine, neuroleptic malignant syndrome, withdrawal effect, schizophreniaCheng MFGu HYZheng LRWang HLZhong ZYWen SLDove Medical PressarticleClozapineNeuroleptic malignant syndromeWithdrawal effectSchizophrenia.Neurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2016, Iss Issue 1, Pp 695-697 (2016) |
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DOAJ |
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Clozapine Neuroleptic malignant syndrome Withdrawal effect Schizophrenia. Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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Clozapine Neuroleptic malignant syndrome Withdrawal effect Schizophrenia. Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Cheng MF Gu HY Zheng LR Wang HL Zhong ZY Wen SL Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia |
description |
Minfeng Cheng,* Huaying Gu,* Liangrong Zheng, Houliang Wang, Zhiyong Zhong, Shenglin Wen Department of Psychiatry, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China *These authors contributed equally to this work Abstract: Here, we report a female patient developing neuroleptic malignant syndrome following the use of a combination of clozapine and haloperidol. Subsequently, the patient presented withdrawal effects after an abrupt discontinuation of clozapine. Psychiatrists not aware of possible clozapine-withdrawal effects may misdiagnose as a part of the primary mental illness or as the initial symptoms worsening, if unrecognized. Keywords: clozapine, neuroleptic malignant syndrome, withdrawal effect, schizophrenia |
format |
article |
author |
Cheng MF Gu HY Zheng LR Wang HL Zhong ZY Wen SL |
author_facet |
Cheng MF Gu HY Zheng LR Wang HL Zhong ZY Wen SL |
author_sort |
Cheng MF |
title |
Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia |
title_short |
Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia |
title_full |
Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia |
title_fullStr |
Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia |
title_full_unstemmed |
Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia |
title_sort |
neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia |
publisher |
Dove Medical Press |
publishDate |
2016 |
url |
https://doaj.org/article/a7ef09e2ad1049538b8fff79fb4ba05b |
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