Functional modulation of phosphodiesterase-6 by calcium in mouse rod photoreceptors

Abstract Phosphodiesterase-6 (PDE6) is a key protein in the G-protein cascade converting photon information to bioelectrical signals in vertebrate photoreceptor cells. Here, we demonstrate that PDE6 is regulated by calcium, contrary to the common view that PDE1 is the unique PDE class whose activity...

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Autores principales: Teemu Turunen, Ari Koskelainen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a800473aa0b54762bc540317f671c048
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