ACTIVATION OF CELLS FROM HYPOTHALAMIC STRUCTURES AFTER INJECTION OF ANTIGENS DIFFERENT IN THEIR NATURE (by the c-Fos expression)

Abstract. Activation levels of hypothalamic structures (AHN, PVH, DMH, VMH, LHA, PH) were analyzed within first hours after injection of antigens [lipopolysaccharide (LPS) and bovine serum albumine [BSA]). For all investigated hypothalamic structures, an increase of c-Fos positive cells numbers was...

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Autores principales: S. V. Perekrest, Yu. V. Gavrilov, T. V. Abramova, N. S. Novikova, E. A. Korneva
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/a80124236e7b4b838a1f227c7cadd943
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spelling oai:doaj.org-article:a80124236e7b4b838a1f227c7cadd9432021-11-18T08:03:42ZACTIVATION OF CELLS FROM HYPOTHALAMIC STRUCTURES AFTER INJECTION OF ANTIGENS DIFFERENT IN THEIR NATURE (by the c-Fos expression)1563-06252313-741X10.15789/1563-0625-2006-5-6-631-636https://doaj.org/article/a80124236e7b4b838a1f227c7cadd9432014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/536https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Activation levels of hypothalamic structures (AHN, PVH, DMH, VMH, LHA, PH) were analyzed within first hours after injection of antigens [lipopolysaccharide (LPS) and bovine serum albumine [BSA]). For all investigated hypothalamic structures, an increase of c-Fos positive cells numbers was observed after injection of the antigens, as compared to the controls. LPS injection caused activation of more multiple neuron populations. AHN, PVH, LHA, and PH structures exhibited the highest levels of c-Fos activation upon LPS application. BSA injection induced activation of lesser cells quantities, but their enrichment in c-Fos protein was higher, thus resulting into increased optical density of VMH, LHA and PH neurons. Hence, the present work has shown that activation pattern of hypothalamic structures differs upon application of antigens that are different by their origin.S. V. PerekrestYu. V. GavrilovT. V. AbramovaN. S. NovikovaE. A. KornevaSPb RAACIarticlec-foshypothalamuslipopolysaccharidebovine serum albumineImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 8, Iss 5-6, Pp 631-636 (2014)
institution DOAJ
collection DOAJ
language RU
topic c-fos
hypothalamus
lipopolysaccharide
bovine serum albumine
Immunologic diseases. Allergy
RC581-607
spellingShingle c-fos
hypothalamus
lipopolysaccharide
bovine serum albumine
Immunologic diseases. Allergy
RC581-607
S. V. Perekrest
Yu. V. Gavrilov
T. V. Abramova
N. S. Novikova
E. A. Korneva
ACTIVATION OF CELLS FROM HYPOTHALAMIC STRUCTURES AFTER INJECTION OF ANTIGENS DIFFERENT IN THEIR NATURE (by the c-Fos expression)
description Abstract. Activation levels of hypothalamic structures (AHN, PVH, DMH, VMH, LHA, PH) were analyzed within first hours after injection of antigens [lipopolysaccharide (LPS) and bovine serum albumine [BSA]). For all investigated hypothalamic structures, an increase of c-Fos positive cells numbers was observed after injection of the antigens, as compared to the controls. LPS injection caused activation of more multiple neuron populations. AHN, PVH, LHA, and PH structures exhibited the highest levels of c-Fos activation upon LPS application. BSA injection induced activation of lesser cells quantities, but their enrichment in c-Fos protein was higher, thus resulting into increased optical density of VMH, LHA and PH neurons. Hence, the present work has shown that activation pattern of hypothalamic structures differs upon application of antigens that are different by their origin.
format article
author S. V. Perekrest
Yu. V. Gavrilov
T. V. Abramova
N. S. Novikova
E. A. Korneva
author_facet S. V. Perekrest
Yu. V. Gavrilov
T. V. Abramova
N. S. Novikova
E. A. Korneva
author_sort S. V. Perekrest
title ACTIVATION OF CELLS FROM HYPOTHALAMIC STRUCTURES AFTER INJECTION OF ANTIGENS DIFFERENT IN THEIR NATURE (by the c-Fos expression)
title_short ACTIVATION OF CELLS FROM HYPOTHALAMIC STRUCTURES AFTER INJECTION OF ANTIGENS DIFFERENT IN THEIR NATURE (by the c-Fos expression)
title_full ACTIVATION OF CELLS FROM HYPOTHALAMIC STRUCTURES AFTER INJECTION OF ANTIGENS DIFFERENT IN THEIR NATURE (by the c-Fos expression)
title_fullStr ACTIVATION OF CELLS FROM HYPOTHALAMIC STRUCTURES AFTER INJECTION OF ANTIGENS DIFFERENT IN THEIR NATURE (by the c-Fos expression)
title_full_unstemmed ACTIVATION OF CELLS FROM HYPOTHALAMIC STRUCTURES AFTER INJECTION OF ANTIGENS DIFFERENT IN THEIR NATURE (by the c-Fos expression)
title_sort activation of cells from hypothalamic structures after injection of antigens different in their nature (by the c-fos expression)
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/a80124236e7b4b838a1f227c7cadd943
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AT tvabramova activationofcellsfromhypothalamicstructuresafterinjectionofantigensdifferentintheirnaturebythecfosexpression
AT nsnovikova activationofcellsfromhypothalamicstructuresafterinjectionofantigensdifferentintheirnaturebythecfosexpression
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