Surface microstructures on planar substrates and textile fibers guide neurite outgrowth: a scaffold solution to push limits of critical nerve defect regeneration?

The treatment of critical size peripheral nerve defects represents one of the most serious problems in neurosurgery. If the gap size exceeds a certain limit, healing can't be achieved. Connection mismatching may further reduce the clinical success. The present study investigates how far specifi...

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Bibliographic Details
Main Authors: Stefan Weigel, Thomas Osterwalder, Ursina Tobler, Li Yao, Manuel Wiesli, Thomas Lehnert, Abhay Pandit, Arie Bruinink
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
R
Q
Online Access:https://doaj.org/article/a801ff84505c4e49b964f104ed48bb9d
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