Vasopressin and oxytocin expression in hypothalamic supraoptic nucleus and plasma electrolytes changes in water-deprived male Meriones libycus

In mammals, plasmatic osmolality needs to be stable, and it is highly related to the hydric state of the animals which depends on the activity of the hypothalamic neurohypophysial system and more particularly by vasopressin secretion. Meriones, a desert rodent, can survive even without drinking for...

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Autores principales:	Lydia Boumansour, Nadir Benhafri, Gilles Guillon, Maithe Corbani, Hanane Touati, Aicha Dekar-Madoui, Saliha Ouali-Hassenaoui
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2021
Materias:	desert rodent dehydration plasmatic osmolality supraoptic nucleus vasopressin Medicine (General) R5-920 Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/a80e364b400448389286e835b8be68d0
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spelling	oai:doaj.org-article:a80e364b400448389286e835b8be68d02021-11-04T15:00:42ZVasopressin and oxytocin expression in hypothalamic supraoptic nucleus and plasma electrolytes changes in water-deprived male Meriones libycus1976-83542151-248510.1080/19768354.2021.1986130https://doaj.org/article/a80e364b400448389286e835b8be68d02021-09-01T00:00:00Zhttp://dx.doi.org/10.1080/19768354.2021.1986130https://doaj.org/toc/1976-8354https://doaj.org/toc/2151-2485In mammals, plasmatic osmolality needs to be stable, and it is highly related to the hydric state of the animals which depends on the activity of the hypothalamic neurohypophysial system and more particularly by vasopressin secretion. Meriones, a desert rodent, can survive even without drinking for more than one month. The mechanism(s) by which they survive under these conditions remains poorly understood. In this study, we examine the water’s deprivation consequences on the: (1) anatomy, morphology, and physiology of the hypothalamic supraoptic nucleus, (2) body mass and plasma electrolytes changes in male desert rodents ‘Meriones libycus’ subjected to water deprivation for 30 days. The effect of water deprivation was evaluated on the structural and cellular organization of the supraoptic nucleus by morphological observations and immunohistochemical approaches, allowing the labeling of AVP but also oxytocin. Our finding demonstrated that upon water deprivation (1) the body weight decreased and reached a plateau after a month of water restriction. (2) The plasmatic osmolality began to decrease and return to values similar to control animals at day 30. (3) The SON, both in hydrated and water-deprived animals, is highly developed.(4) The AVP labeling in the SON increased upon dehydration at variance with OT. These changes observed in body mass and plasma osmolality reveal an important adaptive process of male Meriones in response to prolonged water deprivation. Overall, this animal represents an interesting model for the study of water body homeostasis and the mechanisms underlying the survival of desert rodents to xeric environments.Lydia BoumansourNadir BenhafriGilles GuillonMaithe CorbaniHanane TouatiAicha Dekar-MadouiSaliha Ouali-HassenaouiTaylor & Francis Grouparticledesert rodentdehydrationplasmatic osmolalitysupraoptic nucleusvasopressinMedicine (General)R5-920Biology (General)QH301-705.5ENAnimal Cells and Systems, Vol 25, Iss 5, Pp 337-346 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	desert rodent dehydration plasmatic osmolality supraoptic nucleus vasopressin Medicine (General) R5-920 Biology (General) QH301-705.5
spellingShingle	desert rodent dehydration plasmatic osmolality supraoptic nucleus vasopressin Medicine (General) R5-920 Biology (General) QH301-705.5 Lydia Boumansour Nadir Benhafri Gilles Guillon Maithe Corbani Hanane Touati Aicha Dekar-Madoui Saliha Ouali-Hassenaoui Vasopressin and oxytocin expression in hypothalamic supraoptic nucleus and plasma electrolytes changes in water-deprived male Meriones libycus
description	In mammals, plasmatic osmolality needs to be stable, and it is highly related to the hydric state of the animals which depends on the activity of the hypothalamic neurohypophysial system and more particularly by vasopressin secretion. Meriones, a desert rodent, can survive even without drinking for more than one month. The mechanism(s) by which they survive under these conditions remains poorly understood. In this study, we examine the water’s deprivation consequences on the: (1) anatomy, morphology, and physiology of the hypothalamic supraoptic nucleus, (2) body mass and plasma electrolytes changes in male desert rodents ‘Meriones libycus’ subjected to water deprivation for 30 days. The effect of water deprivation was evaluated on the structural and cellular organization of the supraoptic nucleus by morphological observations and immunohistochemical approaches, allowing the labeling of AVP but also oxytocin. Our finding demonstrated that upon water deprivation (1) the body weight decreased and reached a plateau after a month of water restriction. (2) The plasmatic osmolality began to decrease and return to values similar to control animals at day 30. (3) The SON, both in hydrated and water-deprived animals, is highly developed.(4) The AVP labeling in the SON increased upon dehydration at variance with OT. These changes observed in body mass and plasma osmolality reveal an important adaptive process of male Meriones in response to prolonged water deprivation. Overall, this animal represents an interesting model for the study of water body homeostasis and the mechanisms underlying the survival of desert rodents to xeric environments.
format	article
author	Lydia Boumansour Nadir Benhafri Gilles Guillon Maithe Corbani Hanane Touati Aicha Dekar-Madoui Saliha Ouali-Hassenaoui
author_facet	Lydia Boumansour Nadir Benhafri Gilles Guillon Maithe Corbani Hanane Touati Aicha Dekar-Madoui Saliha Ouali-Hassenaoui
author_sort	Lydia Boumansour
title	Vasopressin and oxytocin expression in hypothalamic supraoptic nucleus and plasma electrolytes changes in water-deprived male Meriones libycus
title_short	Vasopressin and oxytocin expression in hypothalamic supraoptic nucleus and plasma electrolytes changes in water-deprived male Meriones libycus
title_full	Vasopressin and oxytocin expression in hypothalamic supraoptic nucleus and plasma electrolytes changes in water-deprived male Meriones libycus
title_fullStr	Vasopressin and oxytocin expression in hypothalamic supraoptic nucleus and plasma electrolytes changes in water-deprived male Meriones libycus
title_full_unstemmed	Vasopressin and oxytocin expression in hypothalamic supraoptic nucleus and plasma electrolytes changes in water-deprived male Meriones libycus
title_sort	vasopressin and oxytocin expression in hypothalamic supraoptic nucleus and plasma electrolytes changes in water-deprived male meriones libycus
publisher	Taylor & Francis Group
publishDate	2021
url	https://doaj.org/article/a80e364b400448389286e835b8be68d0
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Vasopressin and oxytocin expression in hypothalamic supraoptic nucleus and plasma electrolytes changes in water-deprived male Meriones libycus

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