Integrative analysis reveals RNA G-quadruplexes in UTRs are selectively constrained and enriched for functional associations
G-quadruplexes (G4s) are secondary structures that can form in both DNA and RNA from guanine-rich sequences which are enriched in untranslated regions (UTRs). Here, Lee et al. find that putative G4-forming sequences are evolutionarily constrained, enriched for RNA-binding protein interactions and en...
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Autores principales: | David S. M. Lee, Louis R. Ghanem, Yoseph Barash |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/a81acb8a15f44cb5b34ac2f1cb19717d |
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