Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis

Chiral 1,1-diaryl alkanes are important targets in pharmaceutical industry. Here, the authors report report a redox-neutral enantioselective benzylic C−H bond arylation via photoredox/nickel dual catalysis accessing chiral 1,1-diarylalkane compounds under mild conditions.

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Detalles Bibliográficos
Autores principales:	Xiaokai Cheng, Huangzhe Lu, Zhan Lu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a82023b06903447ca014df5aca9328b6
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spelling	oai:doaj.org-article:a82023b06903447ca014df5aca9328b62021-12-02T17:01:46ZEnantioselective benzylic C–H arylation via photoredox and nickel dual catalysis10.1038/s41467-019-11392-62041-1723https://doaj.org/article/a82023b06903447ca014df5aca9328b62019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11392-6https://doaj.org/toc/2041-1723Chiral 1,1-diaryl alkanes are important targets in pharmaceutical industry. Here, the authors report report a redox-neutral enantioselective benzylic C−H bond arylation via photoredox/nickel dual catalysis accessing chiral 1,1-diarylalkane compounds under mild conditions.Xiaokai ChengHuangzhe LuZhan LuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiaokai Cheng Huangzhe Lu Zhan Lu Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis
description	Chiral 1,1-diaryl alkanes are important targets in pharmaceutical industry. Here, the authors report report a redox-neutral enantioselective benzylic C−H bond arylation via photoredox/nickel dual catalysis accessing chiral 1,1-diarylalkane compounds under mild conditions.
format	article
author	Xiaokai Cheng Huangzhe Lu Zhan Lu
author_facet	Xiaokai Cheng Huangzhe Lu Zhan Lu
author_sort	Xiaokai Cheng
title	Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis
title_short	Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis
title_full	Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis
title_fullStr	Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis
title_full_unstemmed	Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis
title_sort	enantioselective benzylic c–h arylation via photoredox and nickel dual catalysis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/a82023b06903447ca014df5aca9328b6
work_keys_str_mv	AT xiaokaicheng enantioselectivebenzyliccharylationviaphotoredoxandnickeldualcatalysis AT huangzhelu enantioselectivebenzyliccharylationviaphotoredoxandnickeldualcatalysis AT zhanlu enantioselectivebenzyliccharylationviaphotoredoxandnickeldualcatalysis
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Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis

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