Post‐coronavirus disease 2019 organizing pneumonia confirmed pathologically by video‐assisted thoracoscopic surgery
Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2, has become a global pandemic. Many survivors of serious COVID‐19 pneumonia have long‐term residual pulmonary disease. However, there is little documentation of the histopathological characteristi...
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Wiley
2021
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oai:doaj.org-article:a82cc103c61a407fab5ad860ae1f39d72021-11-25T13:46:30ZPost‐coronavirus disease 2019 organizing pneumonia confirmed pathologically by video‐assisted thoracoscopic surgery2051-338010.1002/rcr2.871https://doaj.org/article/a82cc103c61a407fab5ad860ae1f39d72021-12-01T00:00:00Zhttps://doi.org/10.1002/rcr2.871https://doaj.org/toc/2051-3380Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2, has become a global pandemic. Many survivors of serious COVID‐19 pneumonia have long‐term residual pulmonary disease. However, there is little documentation of the histopathological characteristics of lung sequelae post‐COVID‐19 and effective treatments. We present two Japanese cases of lung sequelae post‐COVID‐19. The patients were histopathologically diagnosed with organizing pneumonia (OP) or OP with fibrosis and no diffuse alveolar damage on video‐assisted thoracoscopic surgery. Case 1, who had been diagnosed with OP, was successfully treated with corticosteroid and other immunosuppressive agents over a 6‐month period. Although case 2, who had been diagnosed with OP with fibrosis, had a partial and unsatisfactory response to immunosuppressive agents, the patient responded to antifibrotic treatment including nintedanib.Keishi SuginoHirotaka OnoShuji HaraguchiSeiji IgarashiAkira HebisawaEiyasu TsuboiWileyarticlecoronavirus disease 2019corticosteroidorganizing pneumoniasevere acute respiratory syndrome coronavirus 2video‐assisted thoracoscopic surgeryDiseases of the respiratory systemRC705-779ENRespirology Case Reports, Vol 9, Iss 12, Pp n/a-n/a (2021) |
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DOAJ |
| collection |
DOAJ |
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EN |
| topic |
coronavirus disease 2019 corticosteroid organizing pneumonia severe acute respiratory syndrome coronavirus 2 video‐assisted thoracoscopic surgery Diseases of the respiratory system RC705-779 |
| spellingShingle |
coronavirus disease 2019 corticosteroid organizing pneumonia severe acute respiratory syndrome coronavirus 2 video‐assisted thoracoscopic surgery Diseases of the respiratory system RC705-779 Keishi Sugino Hirotaka Ono Shuji Haraguchi Seiji Igarashi Akira Hebisawa Eiyasu Tsuboi Post‐coronavirus disease 2019 organizing pneumonia confirmed pathologically by video‐assisted thoracoscopic surgery |
| description |
Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2, has become a global pandemic. Many survivors of serious COVID‐19 pneumonia have long‐term residual pulmonary disease. However, there is little documentation of the histopathological characteristics of lung sequelae post‐COVID‐19 and effective treatments. We present two Japanese cases of lung sequelae post‐COVID‐19. The patients were histopathologically diagnosed with organizing pneumonia (OP) or OP with fibrosis and no diffuse alveolar damage on video‐assisted thoracoscopic surgery. Case 1, who had been diagnosed with OP, was successfully treated with corticosteroid and other immunosuppressive agents over a 6‐month period. Although case 2, who had been diagnosed with OP with fibrosis, had a partial and unsatisfactory response to immunosuppressive agents, the patient responded to antifibrotic treatment including nintedanib. |
| format |
article |
| author |
Keishi Sugino Hirotaka Ono Shuji Haraguchi Seiji Igarashi Akira Hebisawa Eiyasu Tsuboi |
| author_facet |
Keishi Sugino Hirotaka Ono Shuji Haraguchi Seiji Igarashi Akira Hebisawa Eiyasu Tsuboi |
| author_sort |
Keishi Sugino |
| title |
Post‐coronavirus disease 2019 organizing pneumonia confirmed pathologically by video‐assisted thoracoscopic surgery |
| title_short |
Post‐coronavirus disease 2019 organizing pneumonia confirmed pathologically by video‐assisted thoracoscopic surgery |
| title_full |
Post‐coronavirus disease 2019 organizing pneumonia confirmed pathologically by video‐assisted thoracoscopic surgery |
| title_fullStr |
Post‐coronavirus disease 2019 organizing pneumonia confirmed pathologically by video‐assisted thoracoscopic surgery |
| title_full_unstemmed |
Post‐coronavirus disease 2019 organizing pneumonia confirmed pathologically by video‐assisted thoracoscopic surgery |
| title_sort |
post‐coronavirus disease 2019 organizing pneumonia confirmed pathologically by video‐assisted thoracoscopic surgery |
| publisher |
Wiley |
| publishDate |
2021 |
| url |
https://doaj.org/article/a82cc103c61a407fab5ad860ae1f39d7 |
| work_keys_str_mv |
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