The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing

Sensory perception and metabolic homeostasis are known to deteriorate with ageing, while mechanisms underlying their deterioration remain poorly understood. Here, the authors demonstrate that decrease of intraflagellar transport in the cilia of sensory neurons impairs sensory perception and metaboli...

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Autores principales:	Yincong Zhang, Xiaona Zhang, Yumin Dai, Mengjiao Song, Yifei Zhou, Jun Zhou, Xiumin Yan, Yidong Shen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a82d93d3e87543e6aedec0ff934e99cf
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spelling	oai:doaj.org-article:a82d93d3e87543e6aedec0ff934e99cf2021-12-02T17:05:49ZThe decrease of intraflagellar transport impairs sensory perception and metabolism in ageing10.1038/s41467-021-22065-82041-1723https://doaj.org/article/a82d93d3e87543e6aedec0ff934e99cf2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22065-8https://doaj.org/toc/2041-1723Sensory perception and metabolic homeostasis are known to deteriorate with ageing, while mechanisms underlying their deterioration remain poorly understood. Here, the authors demonstrate that decrease of intraflagellar transport in the cilia of sensory neurons impairs sensory perception and metabolism in ageing C. elegans.Yincong ZhangXiaona ZhangYumin DaiMengjiao SongYifei ZhouJun ZhouXiumin YanYidong ShenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yincong Zhang Xiaona Zhang Yumin Dai Mengjiao Song Yifei Zhou Jun Zhou Xiumin Yan Yidong Shen The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing
description	Sensory perception and metabolic homeostasis are known to deteriorate with ageing, while mechanisms underlying their deterioration remain poorly understood. Here, the authors demonstrate that decrease of intraflagellar transport in the cilia of sensory neurons impairs sensory perception and metabolism in ageing C. elegans.
format	article
author	Yincong Zhang Xiaona Zhang Yumin Dai Mengjiao Song Yifei Zhou Jun Zhou Xiumin Yan Yidong Shen
author_facet	Yincong Zhang Xiaona Zhang Yumin Dai Mengjiao Song Yifei Zhou Jun Zhou Xiumin Yan Yidong Shen
author_sort	Yincong Zhang
title	The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing
title_short	The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing
title_full	The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing
title_fullStr	The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing
title_full_unstemmed	The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing
title_sort	decrease of intraflagellar transport impairs sensory perception and metabolism in ageing
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a82d93d3e87543e6aedec0ff934e99cf
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The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing

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