Longer telomeres are associated with cancer risk in MMR-proficient hereditary non-polyposis colorectal cancer.
Aberrant telomere length measured in blood has been associated with increased risk of several cancer types. In the field of hereditary non-polyposis colorectal cancer (CRC), and more particularly in Lynch syndrome, caused by germline mutations in the mismatch repair (MMR) genes, we recently found th...
Enregistré dans:
Auteurs principaux: | Nuria Seguí, Elisabet Guinó, Marta Pineda, Matilde Navarro, Fernando Bellido, Conxi Lázaro, Ignacio Blanco, Victor Moreno, Gabriel Capellá, Laura Valle |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2014
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/a8515c67e76b44bb83aa678677b58009 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Telomere length and genetic anticipation in Lynch syndrome.
par: Nuria Seguí, et autres
Publié: (2013) -
Generation of mice with longer and better preserved telomeres in the absence of genetic manipulations
par: Elisa Varela, et autres
Publié: (2016) -
Mice with hyper-long telomeres show less metabolic aging and longer lifespans
par: Miguel A. Muñoz-Lorente, et autres
Publié: (2019) -
Hereditary colorectal cancer syndromes
par: Fernanda Rivera, et autres
Publié: (2020) -
Hereditary cancer in clinical practice
Publié: (2003)