Multi-functional genome-wide CRISPR system for high throughput genotype–phenotype mapping

Genome-scale engineering is generally limited to single methods of alteration such as overexpression, repression or deletion. Here the authors present a tri-functional CRISPR system that can engineer complex synergistic interactions in a genome-wide manner.

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Detalles Bibliográficos
Autores principales: Jiazhang Lian, Carl Schultz, Mingfeng Cao, Mohammad HamediRad, Huimin Zhao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/a8527807c1b148f7874c1327906d4167
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