Onkologie und Bewegung

Onkologie und Bewegung

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Evidence for a protective role of physical activity in cancer prevention is rapidly accumulating. The most convincing epidemiologic data in support of a beneficial effect of physical activity on cancer risk exists for colon, breast, and endometrial cancers. Evidence is weaker for cancers of the lung...

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Autores principales: Schmid D, Steindorf K, Leitzmann MF
Formato: article
Lenguaje:DE
EN
Publicado: Dynamic Media Sales Verlag 2014
Materias:
Sports medicine
RC1200-1245
Acceso en línea:https://doaj.org/article/a85400f5e2ce4b468ca2b0c701090997
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spelling oai:doaj.org-article:a85400f5e2ce4b468ca2b0c7010909972021-11-16T19:01:44ZOnkologie und Bewegung0344-59252510-526410.5960/dzsm.2012.076https://doaj.org/article/a85400f5e2ce4b468ca2b0c7010909972014-01-01T00:00:00Zhttps://www.germanjournalsportsmedicine.com/archive/archive-2014/issue-1/epidemiologic-studies-of-physical-activity-and-primary-prevention-of-cancer/https://doaj.org/toc/0344-5925https://doaj.org/toc/2510-5264Evidence for a protective role of physical activity in cancer prevention is rapidly accumulating. The most convincing epidemiologic data in support of a beneficial effect of physical activity on cancer risk exists for colon, breast, and endometrial cancers. Evidence is weaker for cancers of the lung, pancreas, stomach, prostate, and ovary. Inconsistent findings for a physical activity and cancer relation in the literature may reflect methodologic constraints of available studies, including the use of inaccurate physical activity measurement instruments, failure to assess physical activity performed at etiologically relevant time periods of carcinogenesis, inadequate assessment of the dose of physical activity (frequency, duration, and intensity), incomplete control for potential confounding, and lack of consideration of subgroup findings. These methodologic issues require heightened attention in future studies. Several biologic mechanisms mediate the relation between physical activity and cancer but most etiologic pathways remain poorly understood. Most research on physical activity and primary cancer prevention has been conducted in observational settings, which are not designed to provide evidence of causal associations. controlled physical activity intervention studies of cancer risk are needed to solidify existing mechanistic evidence and to further develop biologic models relating increased physical activity to decreased cancer risk. Key Words: Physical activity, cancer prevention, epidemiology, methodologic considerationsSchmid DSteindorf KLeitzmann MFDynamic Media Sales VerlagarticleSports medicineRC1200-1245DEENDeutsche Zeitschrift für Sportmedizin, Vol 65, Iss 1 (2014)
institution DOAJ
collection DOAJ
language DE
EN
topic Sports medicine
RC1200-1245
spellingShingle Sports medicine
RC1200-1245
Schmid D
Steindorf K
Leitzmann MF
Onkologie und Bewegung
description Evidence for a protective role of physical activity in cancer prevention is rapidly accumulating. The most convincing epidemiologic data in support of a beneficial effect of physical activity on cancer risk exists for colon, breast, and endometrial cancers. Evidence is weaker for cancers of the lung, pancreas, stomach, prostate, and ovary. Inconsistent findings for a physical activity and cancer relation in the literature may reflect methodologic constraints of available studies, including the use of inaccurate physical activity measurement instruments, failure to assess physical activity performed at etiologically relevant time periods of carcinogenesis, inadequate assessment of the dose of physical activity (frequency, duration, and intensity), incomplete control for potential confounding, and lack of consideration of subgroup findings. These methodologic issues require heightened attention in future studies. Several biologic mechanisms mediate the relation between physical activity and cancer but most etiologic pathways remain poorly understood. Most research on physical activity and primary cancer prevention has been conducted in observational settings, which are not designed to provide evidence of causal associations. controlled physical activity intervention studies of cancer risk are needed to solidify existing mechanistic evidence and to further develop biologic models relating increased physical activity to decreased cancer risk. Key Words: Physical activity, cancer prevention, epidemiology, methodologic considerations
format article
author Schmid D
Steindorf K
Leitzmann MF
author_facet Schmid D
Steindorf K
Leitzmann MF
author_sort Schmid D
title Onkologie und Bewegung
title_short Onkologie und Bewegung
title_full Onkologie und Bewegung
title_fullStr Onkologie und Bewegung
title_full_unstemmed Onkologie und Bewegung
title_sort onkologie und bewegung
publisher Dynamic Media Sales Verlag
publishDate 2014
url https://doaj.org/article/a85400f5e2ce4b468ca2b0c701090997
work_keys_str_mv AT schmidd onkologieundbewegung
AT steindorfk onkologieundbewegung
AT leitzmannmf onkologieundbewegung
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