HERG K+ channel-dependent apoptosis and cell cycle arrest in human glioblastoma cells.

HERG K+ channel-dependent apoptosis and cell cycle arrest in human glioblastoma cells.

Glioblastoma (GB) is associated with poor patient survival owing to uncontrolled tumor proliferation and resistance to apoptosis. Human ether-a-go-go-related gene K(+) channels (hERG; Kv11.1, KCNH2) are expressed in multiple cancer cells including GB and control cell proliferation and death. We hypo...

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Autores principales: Ingo Staudacher, Julian Jehle, Kathrin Staudacher, Hans-Werner Pledl, Dieter Lemke, Patrick A Schweizer, Rüdiger Becker, Hugo A Katus, Dierk Thomas
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a8629f74b84f412e92a180c256be423a
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