Comparison of Halothane and Propofol effect on blood pressure and heart rate changes in maintenance of anesthesia

Background and Objective: Propofol is an intravenous anesthetic for induction and maintenance of anesthesia, which its usage is increasing owing to produce a general state of post operative well being, antiemetic effect, rapid onset and recovery. This study was done to compare the effect of halothan...

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Autores principales:	E Alijan Pour, H Al Reza, M Baradaran, M Najafian Ashrafi, A Bijani
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2004
Materias:	maintenance of anesthesia halothane propofol blood pressure heart rate nausea and vomiting recovery Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/a866bb8be0254da7acefd65968140a27
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spelling	oai:doaj.org-article:a866bb8be0254da7acefd65968140a272021-11-10T09:15:56ZComparison of Halothane and Propofol effect on blood pressure and heart rate changes in maintenance of anesthesia1561-41072251-7170https://doaj.org/article/a866bb8be0254da7acefd65968140a272004-01-01T00:00:00Zhttp://jbums.org/article-1-2735-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: Propofol is an intravenous anesthetic for induction and maintenance of anesthesia, which its usage is increasing owing to produce a general state of post operative well being, antiemetic effect, rapid onset and recovery. This study was done to compare the effect of halothane and propofol on blood pressure and heart rate in maintenance of anesthesia. Methods: One hundred patients in ASA class I and II (American Society of Anesthesiologists) 16-60 years old were randomly divided into two groups. Halothane and propofol with continuous IV infusion were used for maintenance of anesthesia in group 1 and 2, respectively. Hemodynamic changes were measured after premedication, 1 minute after intubation and then every 5 minutes but it was recorded to 30 minutes after beginning and end of surgery. In the end of surgery, the patients were taken to recovery room and observed for evaluating nausea and vomiting for one hour and duration of recovery was compared on the basis of visual and verbal response. Findings: Systolic blood pressure during maintenance of anesthesia was similar in two groups, but systolic blood pressure changes (0.037) and heart rate (P=0.009) were different in both groups. Relative frequency of nausea and vomiting was one in propofol group and four in halothane group. First and second recovery time in propofol group were 9.60, 10.52 min and in halothane group were 20.20, 22.90 min, respectively that there was significant difference between them (P=0.000). Conclusion: With regard to cardiovascular changes in maintenance of anesthesia with propofol, halothane and recovery time, propofol is a better choice in cases that rapid recovery time is need or inhalational drug usage is contraindicated.E Alijan PourH Al RezaM BaradaranM Najafian AshrafiA BijaniBabol University of Medical Sciencesarticlemaintenance of anesthesiahalothanepropofolblood pressureheart ratenausea and vomitingrecoveryMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 6, Iss 1, Pp 26-31 (2004)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	maintenance of anesthesia halothane propofol blood pressure heart rate nausea and vomiting recovery Medicine R Medicine (General) R5-920
spellingShingle	maintenance of anesthesia halothane propofol blood pressure heart rate nausea and vomiting recovery Medicine R Medicine (General) R5-920 E Alijan Pour H Al Reza M Baradaran M Najafian Ashrafi A Bijani Comparison of Halothane and Propofol effect on blood pressure and heart rate changes in maintenance of anesthesia
description	Background and Objective: Propofol is an intravenous anesthetic for induction and maintenance of anesthesia, which its usage is increasing owing to produce a general state of post operative well being, antiemetic effect, rapid onset and recovery. This study was done to compare the effect of halothane and propofol on blood pressure and heart rate in maintenance of anesthesia. Methods: One hundred patients in ASA class I and II (American Society of Anesthesiologists) 16-60 years old were randomly divided into two groups. Halothane and propofol with continuous IV infusion were used for maintenance of anesthesia in group 1 and 2, respectively. Hemodynamic changes were measured after premedication, 1 minute after intubation and then every 5 minutes but it was recorded to 30 minutes after beginning and end of surgery. In the end of surgery, the patients were taken to recovery room and observed for evaluating nausea and vomiting for one hour and duration of recovery was compared on the basis of visual and verbal response. Findings: Systolic blood pressure during maintenance of anesthesia was similar in two groups, but systolic blood pressure changes (0.037) and heart rate (P=0.009) were different in both groups. Relative frequency of nausea and vomiting was one in propofol group and four in halothane group. First and second recovery time in propofol group were 9.60, 10.52 min and in halothane group were 20.20, 22.90 min, respectively that there was significant difference between them (P=0.000). Conclusion: With regard to cardiovascular changes in maintenance of anesthesia with propofol, halothane and recovery time, propofol is a better choice in cases that rapid recovery time is need or inhalational drug usage is contraindicated.
format	article
author	E Alijan Pour H Al Reza M Baradaran M Najafian Ashrafi A Bijani
author_facet	E Alijan Pour H Al Reza M Baradaran M Najafian Ashrafi A Bijani
author_sort	E Alijan Pour
title	Comparison of Halothane and Propofol effect on blood pressure and heart rate changes in maintenance of anesthesia
title_short	Comparison of Halothane and Propofol effect on blood pressure and heart rate changes in maintenance of anesthesia
title_full	Comparison of Halothane and Propofol effect on blood pressure and heart rate changes in maintenance of anesthesia
title_fullStr	Comparison of Halothane and Propofol effect on blood pressure and heart rate changes in maintenance of anesthesia
title_full_unstemmed	Comparison of Halothane and Propofol effect on blood pressure and heart rate changes in maintenance of anesthesia
title_sort	comparison of halothane and propofol effect on blood pressure and heart rate changes in maintenance of anesthesia
publisher	Babol University of Medical Sciences
publishDate	2004
url	https://doaj.org/article/a866bb8be0254da7acefd65968140a27
work_keys_str_mv	AT ealijanpour comparisonofhalothaneandpropofoleffectonbloodpressureandheartratechangesinmaintenanceofanesthesia AT halreza comparisonofhalothaneandpropofoleffectonbloodpressureandheartratechangesinmaintenanceofanesthesia AT mbaradaran comparisonofhalothaneandpropofoleffectonbloodpressureandheartratechangesinmaintenanceofanesthesia AT mnajafianashrafi comparisonofhalothaneandpropofoleffectonbloodpressureandheartratechangesinmaintenanceofanesthesia AT abijani comparisonofhalothaneandpropofoleffectonbloodpressureandheartratechangesinmaintenanceofanesthesia
_version_	1718440224463257600

Comparison of Halothane and Propofol effect on blood pressure and heart rate changes in maintenance of anesthesia

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