COMPARISON OF VARIOUS INTRA-ARTICULAR CORTICOSTEROIDS IN KNEE OSTEOARTHRITIS MANAGEMENT

Objective: To compare the intra-articular injections of Methylprednisolone (MP) and Triamcinolone (TC) in relieving mean pain and mean functional improvement in osteoarthritis (OA) knees management. Study Design: Randomized clinical trial. Place and Duration of Study: Outpatient department of...

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Autores principales:	Ammara Arif, Khalil Ahmad, Abdul Jabbar Arif
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2019
Materias:	triamcinolone osteoarthritis corticosteroids methylprednisolone knee joint Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/a87664ec7687410093a0b9f21e9226eb
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spelling	oai:doaj.org-article:a87664ec7687410093a0b9f21e9226eb2021-11-12T06:20:22ZCOMPARISON OF VARIOUS INTRA-ARTICULAR CORTICOSTEROIDS IN KNEE OSTEOARTHRITIS MANAGEMENT0030-96482411-8842https://doaj.org/article/a87664ec7687410093a0b9f21e9226eb2019-04-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2738/2146https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare the intra-articular injections of Methylprednisolone (MP) and Triamcinolone (TC) in relieving mean pain and mean functional improvement in osteoarthritis (OA) knees management. Study Design: Randomized clinical trial. Place and Duration of Study: Outpatient department of Rehabilitation Medicine of Combined Military Hospital Peshawar, from Jan 2016 to Jun 2016. Material and Methods: Two hundred and forty cases with OA knees were selected and randomly divided into two groups of 120 each. Cases of group ‘I’ and ‘II’ were injected with MP and TC respectively. Mean visual analogue score VAS score for pain and mean Lequesne Functional Index Score (LFS) for functional status were evaluated at 6th post-injection week. Results: Mean age of group I was 55.05 ± 2.053 where as that of group II was 54.84 ± 2.082. Group I had 47 (39%) males and 73 (61%) females. Group II had 48 (40%) males and 72 (60%) females. Group I had significantly less mean VAS as compared to group II (9.34 ± 1.858 vs 11.38 ± 1.954) (p<0.001) and less mean LFS (9.34 ± 1.858 vs 11.38 ± 1.954) (p<0.001) after six weeks of injection. MP had significantly better results in patients of 56-60 years of age and male patients because of comparatively less mean VAS and LFS scores (p<0.001). Conclusion: MP is superior to TC in relieving pain and functional improvement in OA knees management.Ammara ArifKhalil AhmadAbdul Jabbar ArifArmy Medical College Rawalpindiarticletriamcinoloneosteoarthritiscorticosteroidsmethylprednisoloneknee jointMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 2, Pp 286-290 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	triamcinolone osteoarthritis corticosteroids methylprednisolone knee joint Medicine R Medicine (General) R5-920
spellingShingle	triamcinolone osteoarthritis corticosteroids methylprednisolone knee joint Medicine R Medicine (General) R5-920 Ammara Arif Khalil Ahmad Abdul Jabbar Arif COMPARISON OF VARIOUS INTRA-ARTICULAR CORTICOSTEROIDS IN KNEE OSTEOARTHRITIS MANAGEMENT
description	Objective: To compare the intra-articular injections of Methylprednisolone (MP) and Triamcinolone (TC) in relieving mean pain and mean functional improvement in osteoarthritis (OA) knees management. Study Design: Randomized clinical trial. Place and Duration of Study: Outpatient department of Rehabilitation Medicine of Combined Military Hospital Peshawar, from Jan 2016 to Jun 2016. Material and Methods: Two hundred and forty cases with OA knees were selected and randomly divided into two groups of 120 each. Cases of group ‘I’ and ‘II’ were injected with MP and TC respectively. Mean visual analogue score VAS score for pain and mean Lequesne Functional Index Score (LFS) for functional status were evaluated at 6th post-injection week. Results: Mean age of group I was 55.05 ± 2.053 where as that of group II was 54.84 ± 2.082. Group I had 47 (39%) males and 73 (61%) females. Group II had 48 (40%) males and 72 (60%) females. Group I had significantly less mean VAS as compared to group II (9.34 ± 1.858 vs 11.38 ± 1.954) (p<0.001) and less mean LFS (9.34 ± 1.858 vs 11.38 ± 1.954) (p<0.001) after six weeks of injection. MP had significantly better results in patients of 56-60 years of age and male patients because of comparatively less mean VAS and LFS scores (p<0.001). Conclusion: MP is superior to TC in relieving pain and functional improvement in OA knees management.
format	article
author	Ammara Arif Khalil Ahmad Abdul Jabbar Arif
author_facet	Ammara Arif Khalil Ahmad Abdul Jabbar Arif
author_sort	Ammara Arif
title	COMPARISON OF VARIOUS INTRA-ARTICULAR CORTICOSTEROIDS IN KNEE OSTEOARTHRITIS MANAGEMENT
title_short	COMPARISON OF VARIOUS INTRA-ARTICULAR CORTICOSTEROIDS IN KNEE OSTEOARTHRITIS MANAGEMENT
title_full	COMPARISON OF VARIOUS INTRA-ARTICULAR CORTICOSTEROIDS IN KNEE OSTEOARTHRITIS MANAGEMENT
title_fullStr	COMPARISON OF VARIOUS INTRA-ARTICULAR CORTICOSTEROIDS IN KNEE OSTEOARTHRITIS MANAGEMENT
title_full_unstemmed	COMPARISON OF VARIOUS INTRA-ARTICULAR CORTICOSTEROIDS IN KNEE OSTEOARTHRITIS MANAGEMENT
title_sort	comparison of various intra-articular corticosteroids in knee osteoarthritis management
publisher	Army Medical College Rawalpindi
publishDate	2019
url	https://doaj.org/article/a87664ec7687410093a0b9f21e9226eb
work_keys_str_mv	AT ammaraarif comparisonofvariousintraarticularcorticosteroidsinkneeosteoarthritismanagement AT khalilahmad comparisonofvariousintraarticularcorticosteroidsinkneeosteoarthritismanagement AT abduljabbararif comparisonofvariousintraarticularcorticosteroidsinkneeosteoarthritismanagement
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COMPARISON OF VARIOUS INTRA-ARTICULAR CORTICOSTEROIDS IN KNEE OSTEOARTHRITIS MANAGEMENT

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