Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells

Whilst pigmentation has been used to identify retinal pigment epithelial (RPE) cells, surface markers for these cells remain unclear. Here, the authors define surface markers for the RPE including CD140b, which help produce hPSC-derived RPE cells at a large scale following a robust, direct and scala...

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Autores principales: Alvaro Plaza Reyes, Sandra Petrus-Reurer, Sara Padrell Sánchez, Pankaj Kumar, Iyadh Douagi, Hammurabi Bartuma, Monica Aronsson, Sofie Westman, Emma Lardner, Helder André, Anna Falk, Emeline F. Nandrot, Anders Kvanta, Fredrik Lanner
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Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/a87b6c42eab14b69bd24544416acca50
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spelling oai:doaj.org-article:a87b6c42eab14b69bd24544416acca502021-12-02T17:32:26ZIdentification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells10.1038/s41467-020-15326-52041-1723https://doaj.org/article/a87b6c42eab14b69bd24544416acca502020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15326-5https://doaj.org/toc/2041-1723Whilst pigmentation has been used to identify retinal pigment epithelial (RPE) cells, surface markers for these cells remain unclear. Here, the authors define surface markers for the RPE including CD140b, which help produce hPSC-derived RPE cells at a large scale following a robust, direct and scalable monolayer differentiation protocol.Alvaro Plaza ReyesSandra Petrus-ReurerSara Padrell SánchezPankaj KumarIyadh DouagiHammurabi BartumaMonica AronssonSofie WestmanEmma LardnerHelder AndréAnna FalkEmeline F. NandrotAnders KvantaFredrik LannerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alvaro Plaza Reyes
Sandra Petrus-Reurer
Sara Padrell Sánchez
Pankaj Kumar
Iyadh Douagi
Hammurabi Bartuma
Monica Aronsson
Sofie Westman
Emma Lardner
Helder André
Anna Falk
Emeline F. Nandrot
Anders Kvanta
Fredrik Lanner
Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells
description Whilst pigmentation has been used to identify retinal pigment epithelial (RPE) cells, surface markers for these cells remain unclear. Here, the authors define surface markers for the RPE including CD140b, which help produce hPSC-derived RPE cells at a large scale following a robust, direct and scalable monolayer differentiation protocol.
format article
author Alvaro Plaza Reyes
Sandra Petrus-Reurer
Sara Padrell Sánchez
Pankaj Kumar
Iyadh Douagi
Hammurabi Bartuma
Monica Aronsson
Sofie Westman
Emma Lardner
Helder André
Anna Falk
Emeline F. Nandrot
Anders Kvanta
Fredrik Lanner
author_facet Alvaro Plaza Reyes
Sandra Petrus-Reurer
Sara Padrell Sánchez
Pankaj Kumar
Iyadh Douagi
Hammurabi Bartuma
Monica Aronsson
Sofie Westman
Emma Lardner
Helder André
Anna Falk
Emeline F. Nandrot
Anders Kvanta
Fredrik Lanner
author_sort Alvaro Plaza Reyes
title Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells
title_short Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells
title_full Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells
title_fullStr Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells
title_full_unstemmed Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells
title_sort identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/a87b6c42eab14b69bd24544416acca50
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