Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa

The main objective to this study is to demonstrate certain aspects of pathological and histochomical changes in the lungs of rabbits experimentaly infected with P.aeruginosa .  Twelve white Newzoland rabbits of 12-16 weeks old were used . they were randomaly divided into two groups. The first gr...

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Autores principales: AL. Kutbi, S. H., M. J. Alwan
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Lenguaje:EN
Publicado: University of Baghdad, College of Veterinary Medicine 2001
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spelling oai:doaj.org-article:a88174ef098f496b95bef13abc6179f52021-11-07T11:36:26ZPathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa10.30539/ijvm.v25i1.11441609-56932410-7409https://doaj.org/article/a88174ef098f496b95bef13abc6179f52001-06-01T00:00:00Zhttps://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1144https://doaj.org/toc/1609-5693https://doaj.org/toc/2410-7409 The main objective to this study is to demonstrate certain aspects of pathological and histochomical changes in the lungs of rabbits experimentaly infected with P.aeruginosa .  Twelve white Newzoland rabbits of 12-16 weeks old were used . they were randomaly divided into two groups. The first group (6 animals ) were given single intraperitoneal, dose of 108 CFU of P. aeruginosa . The second group (6 animals ) maintained as a control and was inoculated with 1 ml of sterial normal saline by the same route of the first group. All the animals were sacrificed on day three post – inoculation.  The pathological exmination showed acute suppurative reaction in pulmonary tissue together with lymphocytic aggregation around airways and blood vessels. The histochomical study revealed that the granules of goblet cells and submucesal glands of the lung in normal rabbits were of neutral mucopolysaecharides and little sialomucin, these substances changed to sulfated acid mucopolysaccharide and sialomucin in the infected animals. AL. Kutbi, S. H.M. J. AlwanUniversity of Baghdad, College of Veterinary MedicinearticlerabbitsPathologicalhistochemicalP.seudomonasVeterinary medicineSF600-1100ENThe Iraqi Journal of Veterinary Medicine, Vol 25, Iss 1 (2001)
institution DOAJ
collection DOAJ
language EN
topic rabbits
Pathological
histochemical
P.seudomonas
Veterinary medicine
SF600-1100
spellingShingle rabbits
Pathological
histochemical
P.seudomonas
Veterinary medicine
SF600-1100
AL. Kutbi, S. H.
M. J. Alwan
Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa
description The main objective to this study is to demonstrate certain aspects of pathological and histochomical changes in the lungs of rabbits experimentaly infected with P.aeruginosa .  Twelve white Newzoland rabbits of 12-16 weeks old were used . they were randomaly divided into two groups. The first group (6 animals ) were given single intraperitoneal, dose of 108 CFU of P. aeruginosa . The second group (6 animals ) maintained as a control and was inoculated with 1 ml of sterial normal saline by the same route of the first group. All the animals were sacrificed on day three post – inoculation.  The pathological exmination showed acute suppurative reaction in pulmonary tissue together with lymphocytic aggregation around airways and blood vessels. The histochomical study revealed that the granules of goblet cells and submucesal glands of the lung in normal rabbits were of neutral mucopolysaecharides and little sialomucin, these substances changed to sulfated acid mucopolysaccharide and sialomucin in the infected animals.
format article
author AL. Kutbi, S. H.
M. J. Alwan
author_facet AL. Kutbi, S. H.
M. J. Alwan
author_sort AL. Kutbi, S. H.
title Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa
title_short Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa
title_full Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa
title_fullStr Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa
title_full_unstemmed Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa
title_sort pathological and histochemical changes in the lungs of rabbits experimentally infected with p.seudomonas aeruginosa
publisher University of Baghdad, College of Veterinary Medicine
publishDate 2001
url https://doaj.org/article/a88174ef098f496b95bef13abc6179f5
work_keys_str_mv AT alkutbish pathologicalandhistochemicalchangesinthelungsofrabbitsexperimentallyinfectedwithpseudomonasaeruginosa
AT mjalwan pathologicalandhistochemicalchangesinthelungsofrabbitsexperimentallyinfectedwithpseudomonasaeruginosa
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