Structure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome

Membrane proteins are inserted co-transnationally through the association between ribosome, the signal recognition particle and its receptor, and the membrane-bound translocon. Here the authors present a cryo-EM reconstruction of this quaternary complex in the activated state and propose a model for...

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Autores principales: Ahmad Jomaa, Yu-Hsien Hwang Fu, Daniel Boehringer, Marc Leibundgut, Shu-ou Shan, Nenad Ban
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/a88b0b8e6ae44a4cbb1867060dff22e0
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spelling oai:doaj.org-article:a88b0b8e6ae44a4cbb1867060dff22e02021-12-02T14:42:23ZStructure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome10.1038/ncomms154702041-1723https://doaj.org/article/a88b0b8e6ae44a4cbb1867060dff22e02017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15470https://doaj.org/toc/2041-1723Membrane proteins are inserted co-transnationally through the association between ribosome, the signal recognition particle and its receptor, and the membrane-bound translocon. Here the authors present a cryo-EM reconstruction of this quaternary complex in the activated state and propose a model for signal sequence transfer to the translocon.Ahmad JomaaYu-Hsien Hwang FuDaniel BoehringerMarc LeibundgutShu-ou ShanNenad BanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ahmad Jomaa
Yu-Hsien Hwang Fu
Daniel Boehringer
Marc Leibundgut
Shu-ou Shan
Nenad Ban
Structure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome
description Membrane proteins are inserted co-transnationally through the association between ribosome, the signal recognition particle and its receptor, and the membrane-bound translocon. Here the authors present a cryo-EM reconstruction of this quaternary complex in the activated state and propose a model for signal sequence transfer to the translocon.
format article
author Ahmad Jomaa
Yu-Hsien Hwang Fu
Daniel Boehringer
Marc Leibundgut
Shu-ou Shan
Nenad Ban
author_facet Ahmad Jomaa
Yu-Hsien Hwang Fu
Daniel Boehringer
Marc Leibundgut
Shu-ou Shan
Nenad Ban
author_sort Ahmad Jomaa
title Structure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome
title_short Structure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome
title_full Structure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome
title_fullStr Structure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome
title_full_unstemmed Structure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome
title_sort structure of the quaternary complex between srp, sr, and translocon bound to the translating ribosome
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/a88b0b8e6ae44a4cbb1867060dff22e0
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